Evidence map›Paper›PMID 36913155›Full record

ArticleThe international journal of cardiovascular imaging2023

Short term outcome of myocarditis and pericarditis following COVID-19 vaccines: a cardiac magnetic resonance imaging study.

Nicola Galea, Giulia Cundari, Emanuele Di Dedda, Cristina Chimenti, Giovanni Donato Aquaro, Andrea Barison, Riccardo Cau, Ernesto Di Cesare, Paolo Di Renzi, Antonio Esposito and 13 more

Open access · hybridFull text read
In one paragraph

Article in The international journal of cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 1 country.

Nicola GaleaDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy. nicola.galea@uniroma1.it.
Giulia CundariDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.
Emanuele Di DeddaDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, 20072, Pieve Emanuele, Milan, Italy.
Cristina ChimentiDepartment of Clinical, Internal, Anesthesiologist and Cardiovascular Sciences, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.
Giovanni Donato AquaroDepartment of Surgical, Academic Radiology, Medical and Molecular Pathology and of Critical Area, University of Pisa, Pisa, Italy.
Andrea BarisonFondazione Toscana Gabriele Monasterio, Pisa, Italy.
Riccardo CauDepartment of Medical Sciences, Radiology Unit, University of Cagliari, Via Università 40, 09124, Cagliari, Italy.
Ernesto Di CesareDepartment of Life, Health and Environmental Sciences, University of L'Aquila, Piazzale Salvatore Tommasi 1, 67100, L'Aquila, Italy.
Paolo Di RenziRadiology Division, Ospedale "San Giovanni Calibita" Fatebenefratelli Isola Tiberina, Via di Ponte Quattro Capi, 39, 00186, Rome, RM, Italy.
Antonio EspositoClinical and Experimental Radiology Unit, Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy.
Riccardo FalettiDepartment of Surgical Sciences, Radiology Unit, University of Turin, Turin, Italy.
Marco GattiDepartment of Surgical Sciences, Radiology Unit, University of Turin, Turin, Italy.
Carlo LiguoriU.O.C. Diagnostica per Immagini. Ospedale del Mare - ASL NA1 Centro, Via Enrico Russo, 80147, Naples, Italy.
Luigi LovatoDepartment of Pediatric and Adult Cardio-Thoracovascular, Onchoematologic and Emergencies Radiology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, via Giuseppe Massarenti, 9, 40138, Bologna, BO, Italy.
Cesare MantiniDepartment of Neuroscience, Imaging and Clinical Sciences, "G.d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 33, 66100, Chieti, Italy.
Caterina Beatrice MontiDepartment of Biomedical Sciences for Health, Università Degli Studi Di Milano, Via Mangiagalli 31, 20133, Milano, Italy.
Anna PalmisanoClinical and Experimental Radiology Unit, Experimental Imaging Center, IRCCS Ospedale San Raffaele, Milan, Italy.
Silvia PradellaDepartment of Emergency Radiology, University Hospital Careggi, Florence, Italy.
Fabrizio RicciDepartment of Neuroscience, Imaging and Clinical Sciences, "G.d'Annunzio" University of Chieti-Pescara, Via dei Vestini, 33, 66100, Chieti, Italy.
Luca SabaDepartment of Medical Sciences, Radiology Unit, University of Cagliari, Via Università 40, 09124, Cagliari, Italy.
Francesco SecchiDepartment of Biomedical Sciences for Health, Università Degli Studi Di Milano, Via Mangiagalli 31, 20133, Milano, Italy.
Carlo CatalanoDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Viale Regina Elena 324, 00161, Rome, Italy.
Marco FranconeDepartment of Biomedical Sciences, Humanitas University, via Rita Levi Montalcini 4, 20072, Pieve Emanuele, Milan, Italy.
Sapienza University of Rome · ITIRCCS Ospedale San Raffaele · ITUniversity of Cagliari · ITUniversity of Chieti-Pescara · ITUniversity of Turin · ITAzienda Ospedaliero-Universitaria Careggi · ITAzienda USL di Bologna · ITFatebenefratelli Hospital · ITFondazione Toscana Gabriele Monasterio · ITHumanitas University · ITIRCCS Humanitas Research Hospital · ITIRCCS Policlinico San Donato · ITUniversity of L'Aquila · ITUniversity of Milan · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate clinical and cardiac magnetic resonance (CMR) short-term follow-up (FU) in patients with vaccine-associated myocarditis, pericarditis or myo-pericarditis (VAMP) following COVID-19 vaccination. We retrospectively analyzed 44 patients (2 women, mean age: 31.7 ± 15.1 years) with clinical and CMR manifestations of VAMP, recruited from 13 large tertiary national centers. Inclusion criteria were troponin raise, interval between the last vaccination dose and onset of symptoms < 25 days and symptoms-to-CMR < 20 days. 29/44 patients underwent a short-term FU-CMR with a median time of 3.3 months. Ventricular volumes and CMR findings of cardiac injury were collected in all exams. Mean interval between the last vaccination dose and the onset of symptoms was 6.2 ± 5.6 days. 30/44 patients received a vaccination with Comirnaty, 12/44 with Spikevax, 1/44 with Vaxzevria and 1/44 with Janssen (18 after the first dose of vaccine, 20 after the second and 6 after the "booster" dose). Chest pain was the most frequent symptom (41/44), followed by fever (29/44), myalgia (17/44), dyspnea (13/44) and palpitations (11/44). At baseline, left ventricular ejection fraction (LV-EF) was reduced in 7 patients; wall motion abnormalities have been detected in 10. Myocardial edema was found in 35 (79.5%) and LGE in 40 (90.9%) patients. Clinical FU revealed symptoms persistence in 8/44 patients. At FU-CMR, LV-EF was reduced only in 2 patients, myocardial edema was present in 8/29 patients and LGE in 26/29. VAMPs appear to have a mild clinical presentation, with self-limiting course and resolution of CMR signs of active inflammation at short-term follow-up in most of the cases.

Indexed as

COVID-19MyocarditisPericarditisAdolescentAdultCOVID-19 VaccinesFemaleHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMiddle AgedPredictive Value of TestsRetrospective StudiesStroke VolumeVentricular Function, LeftYoung AdultCOVID-19 VaccinesCOVID-19Drug interactionMagnetic resonance imagingMyocarditisPericarditisVaccine

Identifiers

PMID36913155
PMCPMC10009344
OpenAlexW4324017688

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read65
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.