Evidence map›Paper›PMID 36914649›Full record

ArticleNature communications2023

Non-falciparum malaria infection and IgG seroprevalence among children under 15 years in Nigeria, 2018.

Camelia Herman, Colleen M Leonard, Perpetua Uhomoibhi, Mark Maire, Delynn Moss, Uwem Inyang, Ado Abubakar, Abiodun Ogunniyi, Nwando Mba, Stacie M Greby and 5 more

Full text read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Multi-Pathogen Surveillance of Acute Febrile Illness in Nigeria Using TaqMan Array Cards: Implementation Successes and Lessons Learned From the SAFIAN Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  3. Article
  4. Review
  5. Serology reveals comparable patterns in the transmission intensities ofFrontiers in cellular and infection microbiology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Circulation of Non-Open forum infectious diseases · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Genetic diversity ofFrontiers in cellular and infection microbiology · 2024
    Article
  16. Dynamics of IgG antibody response againstFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Camelia Herman *Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, 30029, USA.
Colleen M Leonard *Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, 30029, USA.ORCID 0000-0002-1944-693X
Perpetua UhomoibhiNational Malaria Elimination Programme, Federal Ministry of Health, Abuja, Nigeria.
Mark MaireU.S. President's Malaria Initiative, Malaria Branch, Division of Parasitic Diseases and Malaria, U.S. Centers for Disease Control and Prevention, Abuja, Nigeria.
Delynn MossDivision of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30329, USA.
Uwem InyangU.S. President's Malaria Initiative, United States Agency for International Development (USAID), Abuja, Nigeria.ORCID 0000-0001-9570-8324
Ado AbubakarInstitute of Human Virology (IHVN), Abuja, Nigeria.
Abiodun OgunniyiNigeria Centre for Disease Control (NCDC), Abuja, Nigeria.
Nwando MbaNigeria Centre for Disease Control (NCDC), Abuja, Nigeria.
Stacie M GrebyDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
McPaul I OkoyeDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.
Nnaemeka C IriemenamDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Abuja, Nigeria.ORCID 0000-0003-2187-8894
Ibrahim MaikoreWorld Health Organization, Nigeria Country Office, Abuja, Nigeria.
Laura SteinhardtDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, 30029, USA.
Eric RogierDivision of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, 30029, USA. erogier@cdc.gov.ORCID 0000-0001-7375-8304

Funding

World Health Organization 001
6 · The paper itself

Abstract

Plasmodium falciparum (Pf) is the dominant malaria parasite in Nigeria though P. vivax (Pv), P. ovale (Po), and P. malariae (Pm) are also endemic. Blood samples (n = 31,234) were collected from children aged 0-14 years during a 2018 nationwide HIV survey and assayed for Plasmodium antigenemia, Plasmodium DNA, and IgG against Plasmodium MSP1-19 antigens. Of all children, 6.6% were estimated to have Pm infection and 1.4% Po infection with no Pv infections detected. The highest household wealth quintile was strongly protective against infection with Pm (aOR: 0.11, 95% CI: 0.05-0.22) or Po (aOR= 0.01, 0.00-0.10). Overall Pm seroprevalence was 34.2% (95% CI: 33.3-35.2) with lower estimates for Po (12.1%, 11.6-12.5) and Pv (6.3%, 6.0-6.7). Pm seropositivity was detected throughout the country with several local government areas showing >50% seroprevalence. Serological and DNA indicators show widespread exposure of Nigerian children to Pm with lower rates to Po and Pv.

Indexed as

MalariaMalaria, FalciparumMalaria, VivaxPlasmodiumAntigens, ProtozoanChildHumansImmunoglobulin GNigeriaPlasmodium falciparumPlasmodium vivaxSeroepidemiologic StudiesAntigens, ProtozoanImmunoglobulin G

Identifiers

PMID36914649
PMCPMC10011577

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read155
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.