ArticleNature medicine2023
Optimal dietary patterns for prevention of chronic disease.
Article in Nature medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 162 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
162 citing papers in PubMed, 9 syntheses or guidelines pooled it, 238 citations in OpenAlex.
- Dietary Patterns Associated With Anti-inflammatory Effects: An Umbrella Review of Systematic Reviews and Meta-analyses.Nutrition reviews · 2026Pooled it
- Dietary, Food Security and Diabetes Outcomes Associated with Food Is Medicine Programs among Adults with Type 2 Diabetes in the United States: A Rapid Systematic Review.Advances in nutrition (Bethesda, Md.) · 2026Pooled it
- Pooled it
- Association of dietary patterns with osteoporosis risk: a meta-analysis of observational studies.Journal of orthopaedic surgery and research · 2025Pooled it
- Ultra-Processed Food and Chronic Kidney Disease Risk: A Systematic Review, Meta-Analysis, and Recommendations.Nutrients · 2025Pooled it
- Healthy dietary patterns improve sexual function and incontinence symptoms: systematic review and meta-analysis of dietary patterns and dietary interventions.Frontiers in nutrition · 2025Pooled it
- The Association between Dietary Inflammatory Potential and Urologic Cancers: A Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2024Pooled it
- Adherence to the Mediterranean Diet and Risk of Gastric Cancer: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Ecological predictors of daily dietary intake in black adolescents with overweight and obesity in the families improving together (FIT) for weight loss trial.Journal of behavioral medicine · 2026Trial
- Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial.Nature medicine · 2025Trial
- Trial
- Trial
- Discovery of dietary polyphenols targeting the autoinducer-2 quorum sensing system of pathogenic bacteria.Gut microbes · 2026Article
- The Impact of Medically Tailored Meals Interventions on Hospital Utilization in Maryland.AJPM focus · 2026Article
- Association of Adherence to Various Dietary Patterns With Mortality Among Survivors of Myocardial Infarction: A Prospective Cohort Study.Circulation · 2026Article
- Bone Aging and Glycative Stress: Convergent and Divergent Mechanisms Driving Skeletal Deterioration.Cells · 2026Review
- Vitamin D and Health: Establishing Causal Relationships Through Observational Evidence and Hill's Criteria in a Biological Framework.Nutrients · 2026Review
- Healthy Dietary Patterns and Risk of Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Estimated preventable fraction of chronic disease attributed to long-term physical activity and diet quality, independent of body weight: a prospective cohort study of three US cohorts.Lancet regional health. Americas · 2026Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Multiple dietary patterns have been associated with different diseases; however, their comparability to improve overall health has yet to be determined. Here, in 205,852 healthcare professionals from three US cohorts followed for up to 32 years, we prospectively assessed two mechanism-based diets and six diets based on dietary recommendations in relation to major chronic disease, defined as a composite outcome of incident major cardiovascular disease (CVD), type 2 diabetes and cancer. We demonstrated that adherence to a healthy diet was generally associated with a lower risk of major chronic disease (hazard ratio (HR) comparing the 90th with the 10th percentile of dietary pattern scores = 0.58-0.80). Participants with low insulinemic (HR = 0.58, 95% confidence interval (CI) = 0.57, 0.60), low inflammatory (HR = 0.61, 95% CI = 0.60, 0.63) or diabetes risk-reducing (HR = 0.70, 95% CI = 0.69, 0.72) diet had the largest risk reduction for incident major CVD, type 2 diabetes and cancer as a composite and individually. Similar findings were observed across gender and diverse ethnic groups. Our results suggest that dietary patterns associated with markers of hyperinsulinemia and inflammation and diabetes development may inform on future dietary guidelines for chronic disease prevention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.