ArticleBMC plant biology2023
The transcription factor GhWRKY70 from gossypium hirsutum enhances resistance to verticillium wilt via the jasmonic acid pathway.
Article in BMC plant biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- A Fungal Glycoside Hydrolase From Colletotrichum asianum Mini-Chromosomes Targets Host Chitinase to Suppress Plant Immunity.Molecular plant pathology · 2026Article
- MdWRKY61 enhances apple resistance to Colletotrichum fructicola through jasmonic acid signaling pathway.Plant cell reports · 2026Article
- The GhWRKY70-International journal of molecular sciences · 2026Article
- WRKY Transcription Factors: Integral Regulators of Defence Responses to Biotic Stress in Crops.Plant biotechnology journal · 2026Review
- An integrative defense mechanism mediated by GhBsr-d1L7 and GhERD10 confers resistance to Verticillium dahliae in cotton.BMC biology · 2026Article
- Article
- Advances in WRKY regulation of immune responses in medicinal plants.Frontiers in plant science · 2025Review
- Transcriptome profiling and RNA-Seq SNP analysis of reniform nematode (Frontiers in plant science · 2025Article
- A WRKY transcription factor,Frontiers in plant science · 2025Article
- Integrated Transcriptome and sRNAome Analysis Reveals the Molecular Mechanisms ofInternational journal of molecular sciences · 2024Article
- Study on the Function ofInternational journal of molecular sciences · 2024Article
- Function analysis ofFrontiers in plant science · 2023Article
- Interactions betweenFrontiers in plant science · 2023Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe WRKY transcription factors play significant roles in plant growth, development, and defense responses. However, in cotton, the molecular mechanism of most WRKY proteins and their involvement in Verticillium wilt tolerance are not well understood.
resultsGhWRKY70 is greatly up-regulated in cotton by Verticillium dahliae. Subcellular localization suggests that GhWRKY70 is only located in the nucleus. Transcriptional activation of GhWRKY70 further demonstrates that GhWRKY70 function as a transcriptional activator. Transgenic Arabidopsis plants overexpressing GhWRKY70 exhibited better growth performance and higher lignin content, antioxidant enzyme activities and jasmonic acid (JA) levels than wild-type plants after infection with V. dahliae. In addition, the transgenic Arabidopsis resulted in an enhanced expression level of AtAOS1, a gene related to JA synthesis, further leading to a higher JA accumulation compared to the wild type. However, the disease index (DI) values of the VIGS-treated cotton plants with TRV:WRKY70 were also significantly higher than those of the VIGS-treated cotton plants with TRV:00. The chlorophyll and lignin contents of TRV:WRKY70 plants were significantly lower than those of TRV:00 plants. GhAOS1 expression and JA abundance in TRV:WRKY70 plants were decreased. The GhWRKY70 protein was confirmed to bind to the W-box element in the promoter region of GhAOS by yeast one-hybrid assay and transient expression.
conclusionThese results indicate that the GhWRKY70 transcription factor is a positive regulator in Verticillium wilt tolerance of cotton, and may promote the production of JA via regulation of GhAOS1 expression.
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