Evidence mapPaperPMID 36915725Full record

ArticleAmerican journal of translational research2023

Hepatokines fetuin A and fetuin B status in women with/without gestational diabetes mellitus.

Sobhy M Yakout, Samira Hussein, Omar S Al-Attas, Syed D Hussain, Gamal M Saadawy, Nasser M Al-Daghri

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sobhy M YakoutDepartment of Biochemistry, College of Science, King Saud University Riyadh 11451, Kingdom of Saudi Arabia.
Samira HusseinDepartment of Biochemistry, College of Science, King Saud University Riyadh 11451, Kingdom of Saudi Arabia.
Omar S Al-AttasDepartment of Biochemistry, College of Science, King Saud University Riyadh 11451, Kingdom of Saudi Arabia.
Syed D HussainDepartment of Biochemistry, College of Science, King Saud University Riyadh 11451, Kingdom of Saudi Arabia.
Gamal M SaadawyDepartment of Biochemistry, College of Science, King Saud University Riyadh 11451, Kingdom of Saudi Arabia.
Nasser M Al-DaghriDepartment of Biochemistry, College of Science, King Saud University Riyadh 11451, Kingdom of Saudi Arabia.
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess circulating fetuin A and fetuin B levels in participants with and without Gestational Diabetes Mellitus (GDM) and to find out their correlations with other different parameters relating to gestational diabetes in Saudi women.

methodsA total of 123 Saudi pregnant women (N: 46 GDM and N: 77 healthy control) were included in this observational study. Fasting blood samples were collected to assess serum lipids, insulin and fetuin A and fetuin B. Serum fetuin A and fetuin B were quantified by commercially available kits.

resultsThe median value of fetuin A was slight lower in GDM patients [2003 pg/ml (866-3369)] than in the control group [2015 pg/ml (1060-2951)] without significant difference (P=0.95). The median value of fetuin B was also slight lower in GDM patients [3292 ng/ml (782-6740)] than the control group [3514 ng/ml (364-14854)] but without significant difference (P=0.564). There was a significant inverse correlation between fetuin B and total cholesterol in control group.

conclusionsThe present study did not find a significant association between fetuins A and B with GDM or insulin resistance, but there was a significant inverse correlation between fetuin B and total cholesterol in the control group, reflecting good glucose control and adequate use of lipids in the nutrition of the fetus. Further research is required in the future to understand fetuin's role in the progression of GDM in Saudi women.

Indexed as

Fetuin-Afetuin-Bgestational diabetes mellitusSaudi Arabia

Identifiers

PMID36915725
PMCPMC10006815
OpenAlexW4324129648

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.