Evidence map›Paper›PMID 36916310›Full record

ArticleCancer medicine2023

Racial disparities in opioid prescription and pain management among breast cancer survivors.

Sunny Jung Kim, Reuben P Retnam, Arnethea L Sutton, Megan C Edmonds, Dipankar Bandyopadhyay, Vanessa B Sheppard

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Shared decision making in routine oncology appointments with Black patients with lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Sunny Jung KimDepartment of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-6405-162X
Reuben P RetnamTakeda Pharmaceuticals, Virginia, Massachusetts, USA.
Arnethea L SuttonDepartment of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-4398-0278
Megan C EdmondsDivision of General Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.ORCID 0000-0002-0928-3858
Dipankar BandyopadhyayMassey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-5421-1725
Vanessa B SheppardDepartment of Health Behavior and Policy, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0003-2874-6659
Virginia Commonwealth University · USIcahn School of Medicine at Mount Sinai · USTakeda (United States) · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Renato Martins · 1985 to 2026
$51.0M
Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
Training Program in Cancer Prevention and Control for Priority PopulationsT32CA225617 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Guy H Montgomery, JUAN P WISNIVESKY · 2018 to 2026
$2.6M
PREDICTORS OF ADJUVANT ENDOCRINE THERAPY ADHERENCE IN WOMEN WITH BREAST CANCERR01CA154848 · NCI · GEORGETOWN UNIVERSITY · PI SHEPPARD, VANESSA B · 2011 to 2015
$2.5M
NCATS NIH HHS UL1 TR002649NCI NIH HHS P30 CA016059NCI NIH HHS R01 CA154848NCI NIH HHS T32 CA225617
6 · The paper itself

Abstract

backgroundWe examined whether there are racial disparities in pain management, opioid medicine prescriptions, symptom severity, and quality of life constructs in breast cancer survivors.

methodsWe conducted a secondary analysis of longitudinal data from the Women's Hormonal Therapy Initiation and Persistence (WHIP) study (n = 595), a longitudinal study of hormonal receptor-positive breast cancer survivors. Upon study enrollment, patients completed a survey assessing an array of psychological, behavioral, and treatment outcomes, including adjuvant endocrine therapy (AET)-induced symptoms, and provided a saliva biospecimen. Opioid prescription records were extracted from the health maintenance organizations (HMOs) pharmacy database. The final analytic sample included women with complete HMO pharmacy records for 1 year.

resultsThere were 251 eligible patients, of which 169 (67.3%) were White. The average age was 61.09 years old (SD = 11.07). One hundred seventy-two patients (68.5%) had received at least one opioid medication and 37.1% were prescribed opioids longer than 90 days (n = 93). Sixty-four Black patients (78%) had a record of being prescribed with opioids compared to 64% of White patients (n = 108, p = 0.03). Black patients reported worse vasomotor, neuropsychological, and gastrointestinal symptoms, as well as lower quality of life and greater healthcare discrimination than White patients (p's < 0.05). Black patients were more likely to be prescribed opioids for 90 days or longer compared to White patients, when controlling for age, marital status, income, body mass index (BMI), cancer stage, and chemotherapy status (adjusted Odds Ratio = 2.72, p = 0.014).

conclusionFindings indicate that there are racial differences in opioid prescriptions supplied for pain management and symptomatic outcomes. Future research is needed to understand the causes of disparities in cancer pain management and symptomatic outcomes.

Indexed as

Breast NeoplasmsCancer SurvivorsAnalgesics, OpioidDrug PrescriptionsFemaleHealthcare DisparitiesHumansLongitudinal StudiesMiddle AgedPain ManagementQuality of LifeAnalgesics, Opioidcancer patientsopioidspain management disparity

Identifiers

PMID36916310
PMCPMC10225217
OpenAlexW4324128593

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.