Evidence map›Paper›PMID 36916760›Full record

ArticleJournal of biophotonics2023

Depth-resolved attenuation mapping of the human ovary and fallopian tube using optical coherence tomography.

Shuying Li, Hongbo Luo, Sitai Kou, Ian S Hagemann, Quing Zhu

Abstract read
In one paragraph

Article in Journal of biophotonics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuying LiDepartment of Biomedical Engineering, Washington University in St. Louis, 63130, St. Louis, Missouri, USA.ORCID 0000-0003-3253-6304
Hongbo LuoDepartment of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, Missouri, 63130, USA.
Sitai KouDepartment of Biomedical Engineering, Washington University in St. Louis, 63130, St. Louis, Missouri, USA.
Ian S HagemannDepartment of Pathology & Immunology, Washington University School of Medicine, 63110, St. Louis, Missouri, USA.
Quing ZhuDepartment of Biomedical Engineering, Washington University in St. Louis, 63130, St. Louis, Missouri, USA.ORCID 0000-0002-1837-2588

Funding

Coregistered Photoacoustic and Ultrasound Imaging for Ovarian Cancer Diagnosis and Risk ManagementR01CA237664 · NCI · WASHINGTON UNIVERSITY · PI POWELL, MATTHEW A, SIEGEL, CARY L · 2020 to 2024
$2.6M
Improving diagnostic US for reduction of benign breast biopsies using US-guided Optical TomographyR01CA228047 · NCI · WASHINGTON UNIVERSITY · PI POPLACK, STEVEN, ZHU, QUING · 2019 to 2023
$1.9M
Co-registered photoacoustic and ultrasound imaging for non-invasive ovarian canR01CA151570 · NCI · WASHINGTON UNIVERSITY · PI BREWER, MOLLY A., ZHU, QUING · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA151570NCI NIH HHS R01 CA237664NCI NIH HHS R01CA237664
6 · The paper itself

Abstract

Due to the lack of reliable early-diagnostic tools, most ovarian cancers are diagnosed at late stages. Although optical coherence tomography (OCT) has shown promise for identifying diseased ovaries and fallopian tubes at an earlier stage, previous studies either did not provide quantitative scattering mapping or simply used Beer's law to fit the scattering coefficients of each A-line. In this paper, we calculated the pixel-wise attenuation coefficients of ovaries and fallopian tubes in OCT images. Data from 73 freshly excised human ovaries and fallopian tubes from 36 patients have shown that statistical features are statistically different between cancerous ovaries, infundibula, and fimbriae and normal ones.

Indexed as

Fallopian TubesOvarian NeoplasmsFemaleHumansTomography, Optical Coherencecancer assessmentdepth-resolved attenuationfallopian tubeOCTovary

Identifiers

PMID36916760
PMCPMC10656701

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.