Evidence mapPaperPMID 36917822Full record

ReviewAnnual review of neuroscience2023

Cognition from the Body-Brain Partnership: Exaptation of Memory.

György Buzsáki, David Tingley

Abstract readReview
In one paragraph

Review in Annual review of neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Hippocampal Sharp-Wave Ripples Decrease during Physical Actions Including Consummatory Behavior in Immobile Rodents.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Manipulation of interoceptive signaling biases decision making in rhesus macaques.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Review
  11. Article
  12. Visual Perceptual Processing Abnormalities in Body Dysmorphic Disorder.Current topics in behavioral neurosciences · 2025
    Review
  13. Review
  14. Interoceptive Signals Bias Decision Making in Rhesus Macaques.bioRxiv : the preprint server for biology · 2024
    Article
  15. Disentangling the Hippocampal Projectome.Neuroscience bulletin · 2024
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Neuroscience Needs Network Science.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

György BuzsákiNeuroscience Institute and Department of Neurology, NYU Grossman School of Medicine, New York University, New York, NY, USA; email: gyorgy.buzsaki@nyulangone.org.
David TingleyNeuroscience Institute and Department of Neurology, NYU Grossman School of Medicine, New York University, New York, NY, USA; email: gyorgy.buzsaki@nyulangone.org.

Funding

The role of hypothalamic oxytocin signaling in defeat-induced social learningU19NS107616 · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2025 to 2025
$4.5M
Reexamining the Role of Dendrites in Neuronal FunctionRM1NS132981 · COLUMBIA UNIV NEW YORK MORNINGSIDE · 2025 to 2025
$2.6M
Transformation of Neuronal Activity in the Entorhinal-hippocampal-neocortex PathR01MH122391 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GYORGY BUZSAKI, Jayeeta Basu · 2022 to 2024
$1.2M
NIMH NIH HHS R01 MH122391NINDS NIH HHS RM1 NS132981NINDS NIH HHS U19 NS107616
6 · The paper itself

Abstract

Examination of cognition has historically been approached from language and introspection. However, human language-dependent definitions ignore the evolutionary roots of brain mechanisms and constrain their study in experimental animals. We promote an alternative view, namely that cognition, including memory, can be explained by exaptation and expansion of the circuits and algorithms serving bodily functions. Regulation and protection of metabolic and energetic processes require time-evolving brain computations enabling the organism to prepare for altered future states. Exaptation of such circuits was likely exploited for exploration of the organism's niche. We illustrate that exploration gives rise to a cognitive map, and in turn, environment-disengaged computation allows for mental travel into the past (memory) and the future (planning). Such brain-body interactions not only occur during waking but also persist during sleep. These exaptation steps are illustrated by the dual, endocrine-homeostatic and memory, contributions of the hippocampal system, particularly during hippocampal sharp-wave ripples.

Indexed as

HippocampusSleepAnimalsCognitionHumansallostasisbody controlglucose regulationhippocampushomeostasismemorysharp-wave ripples

Identifiers

PMID36917822
PMCPMC10793243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.