Evidence map›Paper›PMID 36922642›Full record

ArticleScientific reports2023

Angiotensin II type 2 receptor activation preserves megalin in the kidney and prevents proteinuria in high salt diet fed rats.

Kalyani Kulkarni, Sanket Patel, Riyasat Ali, Tahir Hussain

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Megalin: A Sidekick or Nemesis of the Kidney?Journal of the American Society of Nephrology : JASN · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kalyani KulkarniDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Health 2, 4349 Martin Luther King Boulevard, Houston, TX, 77204-5037, USA.
Sanket PatelDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Health 2, 4349 Martin Luther King Boulevard, Houston, TX, 77204-5037, USA.
Riyasat AliDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Health 2, 4349 Martin Luther King Boulevard, Houston, TX, 77204-5037, USA.
Tahir HussainDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Health 2, 4349 Martin Luther King Boulevard, Houston, TX, 77204-5037, USA. thussain@central.uh.edu.
University of Houston · US

Funding

Renal Angiotensin ll Receptor Function in ObesityR01DK061578 · NIDDK · UNIVERSITY OF HOUSTON · PI HUSSAIN, TAHIR · 2003 to 2020
$4.3M
Protective Arm of the Renin Angiotensin System in Obese KidneyR01DK117495 · NIDDK · UNIVERSITY OF HOUSTON · PI HUSSAIN, TAHIR · 2018 to 2021
$1.6M
NIDDK NIH HHS R01 DK061578NIDDK NIH HHS R01 DK117495
6 · The paper itself

Abstract

Proteinuria is a risk factor for and consequence of kidney injury. Angiotensin II type 2 receptor (AT

Indexed as

Low Density Lipoprotein Receptor-Related Protein-2ProteinuriaReceptor, Angiotensin, Type 2AnimalsDietGlycogen Synthase Kinase 3 betaKidney GlomerulusObesityRatsRats, ZuckerReceptor, Angiotensin, Type 1Sodium Chloride, DietaryAgtr2 protein, ratGlycogen Synthase Kinase 3 betaLow Density Lipoprotein Receptor-Related Protein-2Lrp2 protein, ratReceptor, Angiotensin, Type 1Receptor, Angiotensin, Type 2Sodium Chloride, Dietary

Identifiers

PMID36922642
PMCPMC10017765
OpenAlexW4327683679

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read57
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.