Evidence map›Paper›PMID 36923532›Full record

ArticleTheranostics2023

Chromothripsis is correlated with reduced cytotoxic immune infiltration and diminished responsiveness to checkpoint blockade immunotherapy.

Han Chu, Zheng Jin, Jia-Nan Cheng, Qingzhu Jia, Bo Zhu, Haoyang Cai

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Interferon Epsilon Loss Is Elusive 9p21 Link to Immune-Cold Tumors, Resistant to Immune Checkpoint Therapy, and Endogenous CXCL9/10 Induction.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Han ChuCenter of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resources and Eco-Environment, College of Life Sciences, Sichuan University, Chengdu, China.
Zheng JinResearch Institute, GloriousMed Clinical Laboratory (Shanghai) Co., Ltd, Shanghai, China.
Jia-Nan ChengDepartment of Oncology, Xinqiao Hospital, Army Medical University, Chongqing, China.
Qingzhu JiaDepartment of Oncology, Xinqiao Hospital, Army Medical University, Chongqing, China.
Bo ZhuDepartment of Oncology, Xinqiao Hospital, Army Medical University, Chongqing, China.
Haoyang CaiCenter of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resources and Eco-Environment, College of Life Sciences, Sichuan University, Chengdu, China.
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsChromothripsisNeoplasmsCD8-Positive T-LymphocytesHumansImmune Checkpoint InhibitorsImmunotherapyTumor MicroenvironmentAntineoplastic AgentsImmune Checkpoint Inhibitorsbiomarkerscheckpoint blockade immunotherapyChromothripsiscytotoxic immune infiltrationresponsiveness

Identifiers

PMID36923532
PMCPMC10008737
OpenAlexW4324009737

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read8
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.