Evidence map›Paper›PMID 36924463›Full record

ArticleAlcohol, clinical & experimental research2023

Changes over time in endorsement of 11 DSM-IV alcohol use disorder (AUD) criteria in young adults with persistent or recurrent AUD in The Collaborative Study on the Genetics of Alcoholism.

Marc A Schuckit, Tom L Smith, George Danko, Jake Tear, Jessica Hennies, Lee Anne Mendoza, Victor Hesselbrock, Howard J Edenberg, Michie Hesselbrock, Kathleen Bucholz and 5 more

Abstract read
In one paragraph

Article in Alcohol, clinical & experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Predictors of symptom course in alcohol use disorder.Alcohol, clinical & experimental research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marc A SchuckitUniversity of California, San Diego, 8950 Villa La Jolla Drive. Suite B-218, La Jolla, California, 92037, USA.ORCID https://orcid.org/0000-0002-2323-7858
Tom L SmithUniversity of California, San Diego, 8950 Villa La Jolla Drive. Suite B-218, La Jolla, California, 92037, USA.
George DankoUniversity of California, San Diego, 8950 Villa La Jolla Drive. Suite B-218, La Jolla, California, 92037, USA.
Jake TearUniversity of California, San Diego, 8950 Villa La Jolla Drive. Suite B-218, La Jolla, California, 92037, USA.
Jessica HenniesUniversity of California, San Diego, 8950 Villa La Jolla Drive. Suite B-218, La Jolla, California, 92037, USA.
Lee Anne MendozaUniversity of California, San Diego, 8950 Villa La Jolla Drive. Suite B-218, La Jolla, California, 92037, USA.
Victor HesselbrockDepartment of Psychiatry, University of Connecticut, 263 Farmington Ave. MC-2103, Farmington, Connecticut, 06030-1410, USA.ORCID https://orcid.org/0000-0002-0495-8641
Howard J EdenbergDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine, 635 Barnhill Drive, MS4063, Indianapolis, Indiana, 46202-5122, USA.ORCID https://orcid.org/0000-0003-0344-9690
Michie HesselbrockDepartment of Psychiatry, University of Connecticut, 263 Farmington Ave. MC-2103, Farmington, Connecticut, 06030-1410, USA.
Kathleen BucholzPsychiatry, Washington Univ. School of Medicine, 4560 Clayton Ave, Suite 1000, Saint Louis, Missouri, 63110, USA.ORCID https://orcid.org/0000-0003-3794-0736
Grace ChanDepartment of Psychiatry, University of Connecticut Health Center, 263 Farmington Ave, MC 2103, Farmington, Connecticut, 06030-2103, USA.ORCID https://orcid.org/0000-0002-1257-6889
Samuel KupermanChild Psychiatry Clinic, UIHC Department of Psychiatry, The University of Iowa, 200 Hawkins Drive RM#2701-C JPP, Iowa City, Iowa, 52242-1057, USA.
Meredith W FrancisDepartment of Psychiatry, Brown School of Social Work, Washington University in Saint Louis, 1 Brookings Drive, Saint Louis, Missouri, 63130, USA.ORCID https://orcid.org/0000-0003-0547-6836
Martin H PlaweckiDepartment of Psychiatry, Indiana University School of Medicine, Goodman Hall, 355 West 16th Street, Suite 4800, Indianapolis, Indiana, 46202, USA.ORCID https://orcid.org/0000-0003-0708-9514
Collaborative Study on the Genetics of Alcoholism (COGA)

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI JAY Arnold TISCHFIELD · 1989 to 2026
$162.7M
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
NIAAA NIH HHS U10 AA008401NIA NIH HHS U24 AG021886
6 · The paper itself

Abstract

backgroundEndorsement of specific Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) alcohol use disorder (AUD) criteria have been shown to change significantly over time in men in their thirties who have persistent or recurrent AUD. However, few studies have documented whether the endorsement of AUD items changes over time in younger individuals or in women. We evaluated changes in the endorsement of AUD criteria in 377 men and women with persistent or recurrent AUD during their twenties.

methodsInformation on AUD-item endorsement over time was available for 223 men and 154 women aged 20-25 with persistent or recurrent AUD in at least three interviews in the Collaborative Study on the Genetics of Alcoholism. The statistical significance of endorsement changes over time was evaluated using the related-sample Cochran's Q test for the full sample and for men and women separately. Additional analyses evaluated sex differences in the patterns of change.

resultsIn the full sample, the predominant pattern was for a significant increase in the rates of endorsement for six of the seven alcohol dependence criteria but not in the four abuse criteria. A similar pattern was seen within men, but women had significant changes in only three of the seven dependence criteria.

conclusionsEndorsement of the seven alcohol dependence criteria among individuals with persistent or recurrent AUD in their twenties generally increased, but few changes were observed in the rates of endorsement of the four abuse criteria. These results are discussed in terms of how they reflect on the nature of AUD and the DSM criteria.

Indexed as

alcoholismdiagnosislongitudinal

Identifiers

PMID36924463
PMCPMC10308878

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.