Evidence map›Paper›PMID 36925651›Full record

ArticleJournal of oncology2023

A Water-Soluble Hydrogen Sulfide Donor Suppresses the Growth of Hepatocellular Carcinoma via Inhibiting the AKT/GSK-3

Shao-Feng Duan, Meng-Meng Zhang, Qian Dong, Bo Yang, Wei Liu, Xin Zhang, Hai-Lan Yu, Shi-Hui Zhang, Nazeer Hussain Khan, Dong-Dong Wu and 2 more

Open access · hybridFull text read
In one paragraph

Article in Journal of oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Emerging roles of hydrogen sulfide-metabolizing enzymes in cancer.Redox report : communications in free radical research · 2024
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Shao-Feng DuanSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Meng-Meng ZhangSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Qian DongSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Bo YangSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Wei LiuSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Xin ZhangSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Hai-Lan YuSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Shi-Hui ZhangSchool of Pharmacy, Henan University, Kaifeng, Henan 475004, China.
Nazeer Hussain KhanHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, China.
Dong-Dong WuHenan International Joint Laboratory for Nuclear Protein Regulation, School of Basic Medical Sciences, Henan University, Kaifeng, Henan 475004, China.ORCID https://orcid.org/0000-0001-6739-8437
Xiao-Ju ZhangDepartment of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan 450003, China.ORCID https://orcid.org/0000-0001-7040-5490
Juan CenKey Laboratory of Natural Medicine and Immune Engineering, School of Pharmacy, Henan University, Kaifeng, Henan 475001, China.ORCID https://orcid.org/0000-0001-8935-5630
Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is a disease with high morbidity, high mortality, and low cure rate. Hyaluronic acid (HA) is widely adopted in tissue engineering and drug delivery. 5-(4-Hydroxyphenyl)-3H-1, 2-dithiol-3-thione (ADT-OH) is one of commonly used H

Identifiers

PMID36925651
PMCPMC10014162
OpenAlexW4323352971

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.