Evidence map›Paper›PMID 36927451›Full record

ArticleCardiovascular diabetology2023

CVOT Summit 2022 Report: new cardiovascular, kidney, and glycemic outcomes.

Oliver Schnell, Tadej Battelino, Richard Bergenstal, Andreas L Birkenfeld, Antonio Ceriello, Alice Cheng, Melanie Davies, Steve Edelman, Thomas Forst, Francesco Giorgino and 26 more

Open access · goldFull text readLetter
In one paragraph

Article in Cardiovascular diabetology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 19 countries.

Oliver SchnellForschergruppe Diabetes e. V., Helmholtz Center Munich, Ingolstaedter Landstraße 1, Neuherberg, 85764, (Munich), Germany. oliver.schnell@lrz.uni-muenchen.de.
Tadej BattelinoUniversity Medical Center, Ljubljana, Slovenia.
Richard BergenstalInternational Diabetes Center at Park Nicollet, Health Partners, Minneapolis, MN, USA.
Andreas L BirkenfeldDepartment of Internal Medicine IV, University Clinic Tübingen, Tübingen, Germany.
Antonio CerielloIRCCS MultiMedica, Milan, Italy.
Alice ChengCredit Valley Hospital, Mississauga, ON, Canada.
Melanie DaviesDiabetes Research Centre, University of Leicester, Leicester, UK.
Steve EdelmanTaking Control of Your Diabetes, Solana Beach, CA, USA.
Thomas ForstCRS Clinical Research Services Mannheim GmbH, Mannheim, Germany.
Francesco GiorginoDepartment of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, Bari, Italy.
Jennifer GreenDivision of Endocrinology, Department of Medicine and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.
Per-Henrik GroopDepartment of Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Samy HadjadjThorax Institute, University Hospital of Nantes, Nantes, France.
Hiddo J L HeerspinkDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Marcus HompeschProSciento Inc., San Diego, CA, USA.
Baruch IzthakClalit Health Services and Technion Faculty of Medicine, Haifa, Israel.
Linong JiPeking University People's Hospital, Xicheng District, Beijing, China.
Naresh KanumilliManchester University Foundation Trust, Manchester, UK.
Boris MankovskyShupyk National Medical Academy of Postgraduate Education, Kiev, Ukraine.
Chantal MathieuDepartment of Endocrinology, Catholic University Leuven, Leuven, Belgium.
Martin MiszonSciarc GmbH, Baierbrunn, Germany.
Reem MustafaDivision of Nephrology and Hypertension, Medical Center, University of Kansas, Kansas City, KS, USA.
Michael NauckDiabetes Division, St. Josef Hospital, Ruhr-University Bochum, Bochum, Germany.
Roberto Pecoits-FilhoPontifical Catholic University of Paraná, Curitiba, Brazil.
Jeremy PettusAltman Clinical and Translational Research Institute (ACTRI), La Jolla, CA, USA.
Kari RantaEli Lilly and Company, Indianapolis, IN, USA.
Helena W RodbardEndocrine and Metabolic Consultants, Rockville, MD, USA.
Peter RossingSteno Diabetes Center Copenhagen, Herlev, Denmark.
Lars RydenDepartment of Medicine K2, Karolinska Institute, Stockholm, Sweden.
Petra-Maria Schumm-DraegerCenter Internal Medicine Fünf Höfe, Munich, Germany.
Scott D SolomonCardiovascular division, Brigham and Women's Hospital, Boston, MA, USA.
Jan ŠkrhaThird Medical Department and Laboratory for Endocrinology and Metabolism, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Pinar TopseverDepartment of Family Medicine, Acıbadem Mehmet Ali Aydınlar University School of Medicine, Istanbul, Turkey.
Tina VilsbøllSteno Diabetes Center Copenhagen, Herlev, Denmark.
John WildingInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK.
Eberhard StandlForschergruppe Diabetes e. V., Helmholtz Center Munich, Ingolstaedter Landstraße 1, Neuherberg, 85764, (Munich), Germany.
Helmholtz Zentrum München · DEAcıbadem Adana Hospital · TRBrigham and Women's Hospital · USCharles University · CZClalit Health Services · ILClinical Research Services · DECredit Valley Hospital · CADuke University · USEli Lilly (United States) · USFolkhälsans Forskningscentrum · FIGentofte Hospital · DKHealthPartners · USHeinrich Heine University Düsseldorf · DEInstitut du Thorax · FRKarolinska Institutet · SEKU Leuven · BELjubljana University Medical Centre · SIManchester University NHS Foundation Trust · GBMultiMedica · ITNIHR Leicester Biomedical Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 8th Cardiovascular Outcome Trial (CVOT) Summit on Cardiovascular, Kidney, and Glycemic Outcomes was held virtually on November 10-12, 2022. Following the tradition of previous summits, this reference congress served as a platform for in-depth discussion and exchange on recently completed outcomes trials as well as key trials important to the cardiovascular (CV) field. This year's focus was on the results of the DELIVER, EMPA-KIDNEY and SURMOUNT-1 trials and their implications for the treatment of heart failure (HF) and chronic kidney disease (CKD) with sodium-glucose cotransporter-2 (SGLT2) inhibitors and obesity with glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonists. A broad audience of primary care physicians, diabetologists, endocrinologists, cardiologists, and nephrologists participated online in discussions on new consensus recommendations and guideline updates on type 2 diabetes (T2D) and CKD management, overcoming clinical inertia, glycemic markers, continuous glucose monitoring (CGM), novel insulin preparations, combination therapy, and reclassification of T2D. The impact of cardiovascular outcomes on the design of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) trials, as well as the impact of real-world evidence (RWE) studies on the confirmation of CVOT outcomes and clinical trial design, were also intensively discussed. The 9th Cardiovascular Outcome Trial Summit will be held virtually on November 23-24, 2023 ( http://www.cvot.org ).

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Renal Insufficiency, ChronicBlood GlucoseBlood Glucose Self-MonitoringGlucagon-Like Peptide-1 Receptor AgonistsHumansHypoglycemic AgentsKidneyBlood GlucoseGlucagon-Like Peptide-1 Receptor AgonistsHypoglycemic AgentsCardiovascular diseaseChronic kidney diseaseDiabetesGIP/GLP-1 receptor agonistHeart failureObesitySGLT2 inhibitor

Identifiers

PMID36927451
PMCPMC10019427
OpenAlexW4327585971

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read118
identifiers read1
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.