Evidence map›Paper›PMID 36930585›Full record

ArticlePloS one2023

Psychometric properties of an innovative smartphone application to investigate the daily impact of hypoglycemia in people with type 1 or type 2 diabetes: The Hypo-METRICS app.

Uffe Søholm, Melanie Broadley, Natalie Zaremba, Patrick Divilly, Giesje Nefs, Jill Carlton, Julia K Mader, Petra Martina Baumann, Mikel Gomes, Gilberte Martine-Edith and 15 more

Open access · goldFull text read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 14 institutions in 8 countries.

Uffe SøholmMedical & Science, Patient Focused Drug Development, Novo Nordisk A/S, Søborg, Denmark.ORCID 0000-0003-0848-9421
Melanie BroadleyDepartment of Psychology, University of Southern Denmark, Odense, Denmark.
Natalie ZarembaFaculty of Life Sciences and Medicine, Department of Diabetes, School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Patrick DivillyFaculty of Life Sciences and Medicine, Department of Diabetes, School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Giesje NefsDepartment of Medical Psychology, Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, the Netherlands.
Jill CarltonSchool of Health and Related Research (ScHARR), University of Sheffield, Sheffield, United Kingdom.ORCID 0000-0002-9373-7663
Julia K MaderDepartment of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria.ORCID 0000-0001-7854-4233
Petra Martina BaumannDivision of Endocrinology & Diabetology, Medical University of Graz, Graz, Austria.ORCID 0000-0002-7665-0929
Mikel GomesDigital Therapeutics, Scientific Modelling, Novo Nordisk A/S, Søborg, Denmark.
Gilberte Martine-EdithFaculty of Life Sciences and Medicine, Department of Diabetes, School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Daniel J PollardSchool of Health and Related Research (ScHARR), University of Sheffield, Sheffield, United Kingdom.
Dajana RathDepartment of Clinical Psychology, University of Duisburg-Essen, Essen, Germany.
Simon HellerDepartment of Oncology and Metabolism, University of Sheffield, Sheffield, United Kingdom.
Ulrik Pedersen-BjergaardDepartment of Endocrinology and Nephrology, Nordsjællands Hospital Hillerød, Hillerød, Denmark.
Rory J McCrimmonSystems Medicine, School of Medicine, University of Dundee, Dundee, United Kingdom.ORCID 0000-0002-3957-1981
Eric RenardDepartment of Endocrinology, Diabetes, Nutrition, Montpellier University Hospital, Montpellier, France.
Mark EvansWelcome Trust-MRC Institute of Metabolic Science and Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Bastiaan de GalanDepartment of Internal Medicine, Radboud University Medical Centre, Nijmegen, the Netherlands.
Thomas ForkmannDepartment of Clinical Psychology, University of Duisburg-Essen, Essen, Germany.
Stephanie A AmielFaculty of Life Sciences and Medicine, Department of Diabetes, School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Christel HendrieckxSchool of Psychology, Deakin University, Geelong, Australia.
Jane SpeightDepartment of Psychology, University of Southern Denmark, Odense, Denmark.
Pratik ChoudharyFaculty of Life Sciences and Medicine, Department of Diabetes, School of Cardiovascular Medicine and Sciences, King's College London, London, United Kingdom.
Frans PouwerDepartment of Psychology, University of Southern Denmark, Odense, Denmark.
Hypo-RESOLVE consortium
King's College London · GBUniversity of Sheffield · GBDeakin University · AUMedical University of Graz · ATRadboud University Nijmegen · NLUniversity of Duisburg-Essen · DEUniversity of Southern Denmark · DKCentre National de la Recherche Scientifique · FRNovo Nordisk (Denmark) · DKSteno Diabetes Centers · DKUniversity of Cambridge · GBUniversity of Copenhagen · DKUniversity of Dundee · GBUniversity of Leicester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to determine the acceptability and psychometric properties of the Hypo-METRICS (Hypoglycemia MEasurement, ThResholds and ImpaCtS) application (app): a novel tool designed to assess the direct impact of symptomatic and asymptomatic hypoglycemia on daily functioning in people with insulin-treated diabetes. MATERIALS AND

methods100 adults with type 1 diabetes mellitus (T1DM, n = 64) or insulin-treated type 2 diabetes mellitus (T2DM, n = 36) completed three daily 'check-ins' (morning, afternoon and evening) via the Hypo-METRICs app across 10 weeks, to respond to 29 unique questions about their subjective daily functioning. Questions addressed sleep quality, energy level, mood, affect, cognitive functioning, fear of hypoglycemia and hyperglycemia, social functioning, and work/productivity. Completion rates, structural validity, internal consistency, and test-retest reliability were explored. App responses were correlated with validated person-reported outcome measures to investigate convergent (rs>±0.3) and divergent (rs<±0.3) validity.

resultsParticipants' mean±SD age was 54±16 years, diabetes duration was 23±13 years, and most recent HbA1c was 56.6±9.8 mmol/mol. Participants submitted mean±SD 191±16 out of 210 possible 'check-ins' (91%). Structural validity was confirmed with multi-level confirmatory factor analysis showing good model fit on the adjusted model (Comparative Fit Index >0.95, Root-Mean-Square Error of Approximation <0.06, Standardized Root-Mean-square Residual<0.08). Scales had satisfactory internal consistency (all ω≥0.5), and high test-retest reliability (rs≥0.7). Convergent and divergent validity were demonstrated for most scales.

conclusionHigh completion rates and satisfactory psychometric properties demonstrated that the Hypo-METRICS app is acceptable to adults with T1DM and T2DM, and a reliable and valid tool to explore the daily impact of hypoglycemia.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2HypoglycemiaMobile ApplicationsAdultAgedHumansInsulinMiddle AgedPsychometricsReproducibility of ResultsSmartphoneSurveys and QuestionnairesInsulin

Identifiers

PMID36930585
PMCPMC10022775
OpenAlexW4327682201

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read80
identifiers read7
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.