Evidence map›Paper›PMID 36932159›Full record

ArticleMolecular psychiatry2023

Does clozapine treat antipsychotic-induced behavioural supersensitivity through glutamate modulation within the striatum?

Prashant Tibrewal, Pramod C Nair, Karen J Gregory, Christopher J Langmead, Sherry Kit Wa Chan, Tarun Bastiampillai

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Prashant TibrewalCramond Clinic, The Queen Elizabeth Hospital, Woodville South, SA, 5011, Australia.
Pramod C NairDiscipline of Clinical Pharmacology, Flinders Health and Medical Research Institute (FHMRI) College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia.ORCID 0000-0002-8630-0121
Karen J GregoryDrug Discovery Biology and ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.
Christopher J LangmeadDrug Discovery Biology and ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC, 3052, Australia.
Sherry Kit Wa ChanDepartment of Psychiatry, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-2712-5826
Tarun BastiampillaiDiscipline of Psychiatry, College of Medicine and Public Health, Flinders University, Adelaide, SA, Australia. tarun.bastiampillai@monash.edu.ORCID 0000-0002-6931-2913
Flinders University · AUMonash University · AUQueen Elizabeth Hospital · AUUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antipsychotic AgentsClozapineCorpus StriatumGlutamic AcidHaloperidolAntipsychotic AgentsClozapineGlutamic AcidHaloperidol

Identifiers

PMID36932159
PMCPMC10575773
OpenAlexW4327811898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.