ArticleNeurobiology of aging2023
Characterizing age- and sex-related differences in brain structure among middle-aged and older Hispanic/Latino adults in the study of Latinos- investigation of neurocognitive aging magnetic resonance imaging (SOL-INCA MRI).
Article in Neurobiology of aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Contribution of Life-Course Socioeconomic Position to Later-Life Brain Volumes in US Hispanic/Latino Adults.Neurology · 2026Article
- Enlarged Perivascular Spaces Among Hispanic and Latino Adults in SOL-INCA-MRI.Journal of the American Heart Association · 2026Article
- No associations between blood pressure and brain volumes in a convenience sample of Hispanic/Latino middle-aged and older adults.Frontiers in aging neuroscience · 2026Article
- Association of tailpipe-related and nontailpipe-related air pollution exposure with neuroimaging outcomes.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Genetic Architecture of Cerebral White Matter Hyperintensities in Diverse Hispanic/Latino Adults.Neurology. Genetics · 2025Article
- Article
- Multimodal Associations of Modifiable Risk Factors on White Matter Injury: The SOL-INCA-MRI Study (HCHS/SOL).Stroke · 2025Article
- Association of Cardiovascular Health With Brain Volume and White Matter Integrity: Results of the SOL-INCA MRI Study.Neurology · 2025Article
- Sleep Disordered Breathing and Subsequent Neuroimaging Markers of Brain Health in Hispanic/Latino Adults.Neurology · 2025Article
- Sex Differences in Progression of Neurodegeneration: The Age, Gene/Environment Susceptibility-Reykjavik Study.Neuro-degenerative diseases · 2025Article
- Intracranial Volume Is Driven by Both Genetics and Early Life Exposures: The SOL-INCA-MRI Study.Ethnicity & disease · 2024Article
- Cardiovascular disease risk exacerbates brain aging among Hispanic/Latino adults in the SOL-INCA-MRI Study.Frontiers in aging neuroscience · 2024Article
- Sleep duration and brain MRI measures: Results from the SOL-INCA MRI study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Neurocognitive profiles are associated with subsequent brain integrity in a sample of Hispanics/Latinos: Findings from the SOL-INCA-MRI study (HCHS/SOL).Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Life's Essential 8 and cerebrovascular disease among Hispanic/Latino adults: findings from the Hispanic Community Health Study/Study of Latinos and Study of Latinos-Investigation of Neurocognitive Aging magnetic resonance imaging cohort.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
19 authors.
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Abstract
Hispanic/Latino adults are a growing segment of the older U.S. population yet are underrepresented in brain aging research. We aimed to characterize brain aging among diverse Hispanic/Latino individuals. Hispanic/Latino individuals (unweighted n = 2273 ages 35-85 years; 56% female) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) population-based study underwent magnetic resonance imaging (MRI) as part of the SOL- Investigation of Neurocognitive Aging MRI (SOL-INCA-MRI) ancillary study (2018-2022). We performed linear regressions to calculate age associations with brain volumes for each outcome (total (global) brain, hippocampal, lateral ventricle, total white matter hyperintensity (WMH), individual cortical lobar, and total cortical gray matter) and tested modification by sex. Older age was associated with smaller gray matter volumes and larger lateral ventricle and WMH volumes. Age-related differences in global brain volumes and gray matter volumes in specific regions (i.e., the hippocampus and temporal and occipital lobes) were less pronounced among women. Our findings warrant further investigation into sex-specific mechanisms of brain aging using longitudinal studies.
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