Evidence map›Paper›PMID 36936475›Full record

SynthesisFrontiers in immunology2022

Mechanismbased role of the intestinal microbiota in gestational diabetes mellitus: A systematic review and meta-analysis.

Min Yan, Xiaoying Guo, Guiyuan Ji, Rui Huang, Dongyi Huang, Zhifeng Li, Dantao Zhang, Siyi Chen, Rong Cao, Xingfen Yang and 1 more

Open access · goldFull text readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Min YanSchool of Public Health, Southern Medical University, Guangzhou, China.
Xiaoying GuoSchool of Public Health, Southern Medical University, Guangzhou, China.
Guiyuan JiGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Rui HuangGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Dongyi HuangSchool of Public Health, Southern Medical University, Guangzhou, China.
Zhifeng LiGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Dantao ZhangGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Siyi ChenGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Rong CaoGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
Xingfen YangSchool of Public Health, Southern Medical University, Guangzhou, China.
Wei WuSchool of Public Health, Southern Medical University, Guangzhou, China.
Guangdong Provincial Center for Disease Control and Prevention · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Metabolic disorders caused by intestinal microbial dysregulation are considered to be important causes of gestational diabetes mellitus (GDM). Increasing evidence suggests that the diversity and composition of gut microbes are altered in disease states, yet the critical microbes and mechanisms of disease regulation remain unidentified. Methods: PubMed Results: A total of 22 studies were included in this review, involving a total of 965 GDM patients and 1,508 healthy control participants. Alpha diversity did not differ between the participant groups, but beta diversity was significantly different. Conclusion: Enterobacterial profiles were significantly different between the GDM and non-GDM populations. Alpha diversity in patients with GDM is similar to that in healthy people, but beta diversity is significantly different.

Indexed as

Diabetes, GestationalGastrointestinal MicrobiomeMicrobiotaBacteriaFemaleHumansNetherlandsPregnancyUnited Statesgestational diabetes mellitusgut microbiotainsulin resistancemeta-analysissystematic review

Identifiers

PMID36936475
PMCPMC10020587
OpenAlexW4323044888

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read65
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.