Evidence mapPaperPMID 36936697Full record

ArticleFrontiers in cell and developmental biology2023

Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity.

Man Zhang, J Michael Salbaum, Sydney Jones, David Burk, Claudia Kappen

Open access · goldFull text read
In one paragraph

Article in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. CombinedActa biochimica et biophysica Sinica · 2025
    Article
  3. Review
  4. Article
  5. Maternal metabolism influences neural tube closure.Trends in endocrinology and metabolism: TEM · 2023
    Review
  6. Differential responses to maternal diabetes in embryo and visceral yolk sac.Frontiers in cell and developmental biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Man ZhangDevelopmental Biology, Baton Rouge, LA, United States.
J Michael SalbaumRegulation of Gene Expression, Baton Rouge, LA, United States.
Sydney JonesRegulation of Gene Expression, Baton Rouge, LA, United States.
David BurkCell Biology and Bioimaging Core, Baton Rouge, LA, United States.
Claudia KappenDevelopmental Biology, Baton Rouge, LA, United States.

Funding

The role of maternal obesity-driven inflammation and adverse pregnancy outcomes in a mouse model of preeclampsiaP20GM135002 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2022 to 2025
$6.5M
Pilot and Feasibility ProgramP30DK072476 · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2005 to 2025
$2.2M
MOLECULAR MECHANISMS IN DIABETIC EMBRYOPATHYR01HD037804 · UNIVERSITY OF NEBRASKA MEDICAL CENTER · 1998 to 2005
$1.2M
Epigenetic Mechanisms in Diabetic EmbryopathyR01HD086604 · NICHD · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Claudia T Kappen · 2021 to 2021
$543k
NICHD NIH HHS R01 HD037804NICHD NIH HHS R01 HD055528NICHD NIH HHS R01 HD085017NICHD NIH HHS R01 HD086604NIDDK NIH HHS P30 DK072476NIGMS NIH HHS P20 GM103528NIGMS NIH HHS P20 GM135002NIGMS NIH HHS P30 GM118430
6 · The paper itself

Abstract

Maternal diabetes and obesity in pregnancy are well-known risk factors for structural birth defects, including neural tube defects and congenital heart defects. Progeny from affected pregnancies are also predisposed to developing cardiometabolic disease in later life. Based upon

Indexed as

hyperglycemiahyperglycemichyperlipidemialipid deficiencylipid dropletlipid transporterneural tube defect

Identifiers

PMID36936697
PMCPMC10014468
OpenAlexW4322745137

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read40
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.