Evidence mapPaperPMID 36943403Full record

ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2023

Acute kidney injury in diabetes mellitus: Epidemiology, diagnostic, and therapeutic concepts.

Yuan Gui, Zachary Palanza, Haiyan Fu, Dong Zhou

Open access · bronzeAbstract readReview
In one paragraph

Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yuan GuiDivision of Nephrology, Department of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, 06030, USA.
Zachary PalanzaDivision of Nephrology, Department of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, 06030, USA.
Haiyan FuState Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney, Disease, Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Dong ZhouDivision of Nephrology, Department of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, 06030, USA.ORCID https://orcid.org/0000-0003-1981-8745
University of Connecticut · USUniversity of Pittsburgh · US

Funding

Importance of cell-matrix interactions in kidney repair after acute kidney injuryR01DK132059 · NIDDK · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · 2024 to 2025
$906k
The formation of kidney local microenvironment after acute kidney injury.R03DK128529 · NIDDK · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Dong Zhou · 2022 to 2022
$123k
NIDDK NIH HHS K01 DK116816NIDDK NIH HHS R01 DK132059NIDDK NIH HHS R03 DK128529
6 · The paper itself

Abstract

Acute kidney injury (AKI) and diabetes mellitus (DM) are public health problems that cause a high socioeconomic burden worldwide. In recent years, the landscape of AKI etiology has shifted: Emerging evidence has demonstrated that DM is an independent risk factor for the onset of AKI, while an alternative perspective considers AKI as a bona fide complication of DM. Therefore, it is necessary to systematically characterize the features of AKI in DM. In this review, we summarized the epidemiology of AKI in DM. While focusing on circulation- and tissue-specific microenvironment changes after DM, we described the active cellular and molecular mechanisms of increased kidney susceptibility to AKI under DM stress. We also reviewed the current diagnostic and therapeutic strategies for AKI in DM recommended in the clinic. Updated recognition of the epidemiology, pathophysiology, diagnosis, and medications of AKI in DM is believed to reveal a path to mitigate the frequency of AKI and DM comorbidity that will ultimately improve the quality of life in DM patients.

Indexed as

Acute Kidney InjuryDiabetes MellitusHumansKidneyQuality of LifeRisk Factorsacute kidney injurydiabetes mellitusdiagnostic and therapeutic conceptsepidemiologymicroenvironment

Identifiers

PMID36943403
PMCPMC10602403
OpenAlexW4328048819

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.