Evidence mapPaperPMID 36944778Full record

ArticleChild psychiatry and human development2024

An Overview of Pharmacotherapy in the Management of Children with Autism Spectrum Disorder at a Public Hospital in KwaZulu-Natal.

Jennal Maniram, Frasia Oosthuizen, Saira B S Karrim

Open access · hybridAbstract read
In one paragraph

Article in Child psychiatry and human development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Clinical profile of children and adolescents with autism spectrum disorder in Durban, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jennal ManiramSchool of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa. Jennalmaniram@gmail.com.
Frasia OosthuizenSchool of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Saira B S KarrimSchool of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
University of KwaZulu-Natal · ZAAfrica Health Research Institute · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents an overview of prescribing patterns and provides insight into the current management practice for the core symptoms and comorbidities of ASD in children. A quantitative retrospective study was conducted at a public hospital in KwaZulu-Natal, South Africa by reviewing patient files of children diagnosed with ASD and meeting the inclusion criteria for the study. A descriptive analysis of data was done to identify treatment trends and patient therapeutic outcomes. A total of 181 children met the inclusion criteria of the study. Risperidone was the most frequently prescribed drug (88%) for the management of comorbidities and/or core symptoms of ASD. Drugs prescribed to manage ASD comorbidities included methylphenidate, melatonin, sodium valproate, risperidone, oxybutynin, carbamazepine, and others. Except for risperidone, there were no additional drugs that targeted the core symptoms of ASD. Non-pharmacological therapies were often used collaboratively with medication to manage ASD symptoms. In 41% of patients, there were improvements in their symptoms.

Indexed as

Autism Spectrum DisorderHospitals, PublicAdolescentAntipsychotic AgentsChildChild, PreschoolComorbidityFemaleHumansMalePractice Patterns, Physicians'Retrospective StudiesRisperidoneSouth AfricaAntipsychotic AgentsRisperidoneAutismComorbidityCore symptomPharmacotherapyTherapeutic outcome

Identifiers

PMID36944778
PMCPMC11485179
OpenAlexW4353021635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.