ReviewProceedings. Biological sciences2023
Shared reproductive disruption, not neural crest or tameness, explains the domestication syndrome.
Review in Proceedings. Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Harnessing adaptive alleles in native animals for sustainable intensification of livestock.Animal frontiers : the review magazine of animal agriculture · 2026Article
- Mating system of free-ranging domestic dogs and its consequences for dog evolution.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dogs of War: The Effect of War-Inflicted Environmental Damage on Free-Ranging Domestic Dogs.Evolutionary applications · 2025Article
- Long-term synchronous changes in body size among domesticated and wild species.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Review
- The domestication of the wolf larynx-testing the neural crest connection.Royal Society open science · 2025Article
- Hominin Population Structure, Mating Systems, and Intrasexual Competition : Implications for Craniofacial Robusticity and the Self-Domestication Hypothesis.Human nature (Hawthorne, N.Y.) · 2025Article
- The domestication of the larynx: The neural crest connection.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024Article
- Domestication is associated with increased interspecific hybrid compatibility in landfowl (order: Galliformes).The Journal of heredity · 2024Article
- Association of tameness and sociability but no sign of domestication syndrome in mice selectively bred for active tameness.Genes, brain, and behavior · 2024Article
- Developmental bias as a cause and consequence of adaptive radiation and divergence.Frontiers in cell and developmental biology · 2024Review
- Scleral appearance is not a correlate of domestication in mammals.Zoological letters · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Altered neural crest cell (NCC) behaviour is an increasingly cited explanation for the domestication syndrome in animals. However, recent authors have questioned this explanation, while others cast doubt on whether domestication syndrome even exists. Here, we review published literature concerning this syndrome and the NCC hypothesis, together with recent critiques of both. We synthesize these contributions and propose a novel interpretation, arguing shared trait changes under ancient domestication resulted primarily from shared disruption of wild reproductive regimes. We detail four primary selective pathways for 'reproductive disruption' under domestication and contrast these succinct and demonstrable mechanisms with cryptic genetic associations posited by the NCC hypothesis. In support of our perspective, we illustrate numerous important ways in which NCCs contribute to vertebrate reproductive phenotypes, and argue it is not surprising that features derived from these cells would be coincidentally altered under major selective regime changes, as occur in domestication. We then illustrate several pertinent examples of Darwin's 'unconscious selection' in action, and compare applied selection and phenotypic responses in each case. Lastly, we explore the ramifications of reproductive disruption for wider evolutionary discourse, including links to wild 'self-domestication' and 'island effect', and discuss outstanding questions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.