Evidence map›Paper›PMID 36946374›Full record

ArticleRenal failure2023

Plasma soluble tumor necrosis factor receptor I as a biomarker of lupus nephritis and disease activity in systemic lupus erythematosus patients.

Xin-Ran Liu, Yuan-Yuan Qi, Ya-Fei Zhao, Yan Cui, Zhan-Zheng Zhao

Open access · goldFull text read
In one paragraph

Article in Renal failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Association ofJournal of clinical medicine · 2025
    Article
  3. Biomarkers for systemic lupus erythematosus: A scoping review.Immunity, inflammation and disease · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xin-Ran LiuNephrology Hospital, the First Affiliated Hospital of Zhengzhou University, Henan, China.
Yuan-Yuan QiNephrology Hospital, the First Affiliated Hospital of Zhengzhou University, Henan, China.
Ya-Fei ZhaoNephrology Hospital, the First Affiliated Hospital of Zhengzhou University, Henan, China.
Yan CuiNephrology Hospital, the First Affiliated Hospital of Zhengzhou University, Henan, China.
Zhan-Zheng ZhaoNephrology Hospital, the First Affiliated Hospital of Zhengzhou University, Henan, China.
Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe goal of our study was to evaluate the potential role of sTNF-RI as a biomarker of renal involvement in SLE patients and active SLE.

methodsThe study sample consisted of two cohorts. The discovery cohort included 16 SLE patients without renal involvement (non-LN), 60 lupus nephritis (LN) patients and 21 healthy controls (HCs) and the replication cohort included 18 SLE non-LN patients, 116 LN patients and 36 HCs.

resultsThe sTNF-RI levels differed significantly in the discovery cohort. The plasma sTNF-RI levels were higher in LN patients than in non-LN patients (

conclusionsPlasma sTNF-RI might be a good biomarker of renal involvement and disease activity in SLE patients.

Indexed as

Lupus Erythematosus, SystemicLupus NephritisBiomarkersHumansKidneyReceptors, Tumor Necrosis FactorBiomarkersReceptors, Tumor Necrosis Factordisease activitylupus nephritisSystemic lupus erythematosustumor necrosis factor receptor

Identifiers

PMID36946374
PMCPMC10035946
OpenAlexW4353016862

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read84
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.