Evidence map›Paper›PMID 36947702›Full record

ArticleAging2023

RNA virus-mediated changes in organismal oxygen consumption rate in young and old

Eli Hagedorn, Dean Bunnell, Beate Henschel, Daniel L Smith, Stephanie Dickinson, Andrew W Brown, Maria De Luca, Ashley N Turner, Stanislava Chtarbanova

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Eli HagedornDepartment of Biological Sciences, University of Alabama, Tuscaloosa, AL 35401, USA.
Dean BunnellDepartment of Biological Sciences, University of Alabama, Tuscaloosa, AL 35401, USA.
Beate HenschelDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Biostatistics Consulting Center, Bloomington, IN 47405, USA.
Daniel L SmithDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Stephanie DickinsonDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Biostatistics Consulting Center, Bloomington, IN 47405, USA.
Andrew W BrownDepartment of Applied Health Sciences, Indiana University, School of Public Health-Bloomington, Bloomington, IN 47405, USA.
Maria De LucaDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Ashley N TurnerDepartment of Biology, Jacksonville State University, Jacksonville, AL 36265, USA.
Stanislava ChtarbanovaDepartment of Biological Sciences, University of Alabama, Tuscaloosa, AL 35401, USA.
University of Alabama at Birmingham · USIndiana University Bloomington · USIndiana University School of MedicineJacksonville State University · USUniversity of Alabama · USUniversity of Arkansas for Medical Sciences · US

Funding

Sex hormones and arthritis in a long lived animal modelP30AG050886 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jianhua Zhang · 2015 to 2026
$11.3M
Nathan Shock Centers Coordinating CenterU24AG056053 · NIA · AMERICAN FEDERATION FOR AGING RESEARCH · PI STEVEN N. AUSTAD, Stephanie Lederman · 2017 to 2026
$6.1M
Genetic Basis of Lifespan and Healthspan Extension by ACE Inhibition in DrosophilaR01AG073181 · NIA · CLEMSON UNIVERSITY · PI Robert R. H Anholt, MARIA DE LUCA · 2022 to 2026
$2.4M
Strengthening Causal Inference in Behavioral Obesity ResearchR25HL124208 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ALLISON, DAVID B, BROWN, ANDREW W · 2014 to 2023
$1.8M
The Mathematical Sciences in Obesity ResearchR25DK099080 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAVID B ALLISON, Andrew W Brown · 2013 to 2026
$1.2M
Temporal responses in host-virus interactionsR15AI169146 · NIAID · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI CHTARBANOVA, STANISLAVA · 2023 to 2023
$447k
NHLBI NIH HHS R25 HL124208NIAID NIH HHS R15 AI169146NIA NIH HHS P30 AG050886NIA NIH HHS R01 AG073181NIA NIH HHS U24 AG056053NIDDK NIH HHS R25 DK099080
6 · The paper itself

Abstract

Aging is accompanied by increased susceptibility to infections including with viral pathogens resulting in higher morbidity and mortality among the elderly. Significant changes in host metabolism can take place following virus infection. Efficient immune responses are energetically costly, and viruses divert host molecular resources to promote their own replication. Virus-induced metabolic reprogramming could impact infection outcomes, however, how this is affected by aging and impacts organismal survival remains poorly understood. RNA virus infection of

Indexed as

NodaviridaeRNA VirusesVirus DiseasesAnimalsDrosophila melanogasterMaleOxygen ConsumptionagingDrosophila melanogastermetabolismsingle-fly respirometryvirus infection

Identifiers

PMID36947702
PMCPMC10085608
OpenAlexW4353055700

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.