Evidence map›Paper›PMID 36949325›Full record

ReviewAdvances in experimental medicine and biology2023

Ketogenic Diet and Inflammation: Implications for Mood and Anxiety Disorders.

Roy El Karkafi, Tammy Gebara, Michael Salem, Jessica Kamel, Ghinwa El Khoury, Marilynn Zalal, Marc Fakhoury

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Roy El KarkafiDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Tammy GebaraDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Michael SalemDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Jessica KamelDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Ghinwa El KhouryDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Marilynn ZalalDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
Marc FakhouryDepartment of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon. marc.fakhoury@lau.edu.lb.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ketogenic diet, known as a low-carbohydrate, high-protein, and high-fat diet, drastically restrains the major source of energy for the body, forcing it to burn all excess fat through a process called ketosis-the breaking down of fat into ketone bodies. First suggested as a medical treatment for children suffering from epilepsy, this diet has gained increased popularity as a rapid weight loss strategy. Over the past few years, there have been numerous studies suggesting that the ketogenic diet may provide therapeutic effects for several psychiatric conditions such as mood- and anxiety-related disorders. However, despite significant progress in research, the mechanisms underlying its therapeutic effects remain largely unexplored and are yet to be fully elucidated. This chapter provides an in-depth overview of preclinical and clinical evidence supporting the use of a ketogenic diet in the management of mood and anxiety disorders and discusses its relationship with inflammatory processes and potential mechanisms of actions for its therapeutic effects.

Indexed as

Diet, KetogenicAnxiety DisordersChildDiet, High-FatHumansInflammationKetone BodiesKetone BodiesAnxietyBipolar disorderInflammationKetogenic dietMajor depressive disorderMood disordersSchizophrenia

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.