Evidence map›Paper›PMID 36949708›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2023

[Abnormal Activation of T Cells in HIV-1 Infection After Antiretroviral Therapy].

Yue Guo, Yan-Lin Zhang, Dan Zhu, Fang-Hong Gong, Yu-Shuang Gao, Kun-Rong Zhu, Shan-Shan Li

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yue GuoDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Yan-Lin ZhangDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Dan ZhuDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Fang-Hong GongDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Yu-Shuang GaoDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Kun-Rong ZhuDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Shan-Shan LiDepartment of STD and AIDS Laboratory, Chengdu Center for Disease Control and Prevention, Chengdu 610041, China.
Chengdu Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the relationship between abnormal activation of T cell subsets in peripheral whole blood and the recovery of immune function in persons infected with HIV-1, and to examine the relationship between the size of the viral reservoir of HIV-1 DNA and T cell subsets. Methods: HIV-1-infected persons who underwent routine testing between July 2019 and May 2020 were the target population of the study. According to whether, at the time of enrollment, their CD4 Results: The proportions of activated CD4 Conclusion: HIV-1 infected persons have varying degrees of abnormal immune activation of T cell subsets. The abnormal activation of some T-cell subsets is partly associated with the subsequent recovery of immune functions and the size of the viral reservoir of HIV-1 DNA was not associated with the T cell subsets.

Indexed as

HIV-1HIV InfectionsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesHumansT-Lymphocyte SubsetsViral LoadHIV-1HIV DNAImmune activationT cells

Identifiers

PMID36949708
PMCPMC10409166
OpenAlexW4360600854

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.