Evidence mapPaperPMID 36950518Full record

ArticlePhotoacoustics2023

Skeletal muscle optoacoustics reveals patterns of circulatory function and oxygen metabolism during exercise.

Angelos Karlas, Nikolina-Alexia Fasoula, Nikoletta Katsouli, Michael Kallmayer, Sabine Sieber, Sebastian Schmidt, Evangelos Liapis, Martin Halle, Hans-Henning Eckstein, Vasilis Ntziachristos

Open access · goldFull text read
In one paragraph

Article in Photoacoustics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Angelos KarlasInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany.
Nikolina-Alexia FasoulaInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany.
Nikoletta KatsouliInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany.
Michael KallmayerDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Sabine SieberDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Sebastian SchmidtDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Evangelos LiapisInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany.
Martin HalleDZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Hans-Henning EcksteinDepartment for Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Vasilis NtziachristosInstitute of Biological and Medical Imaging, Helmholtz Zentrum München, Neuherberg, Germany.
Klinikum rechts der Isar · DEHelmholtz Zentrum München · DEInstitute of Biological and Medical ImagingTechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging skeletal muscle function and metabolism, as reported by local hemodynamics and oxygen kinetics, can elucidate muscle performance, severity of an underlying disease or outcome of a treatment. Herein, we used multispectral optoacoustic tomography (MSOT) to image hemodynamics and oxygen kinetics within muscle during exercise. Four healthy volunteers underwent three different hand-grip exercise challenges (60s isometric, 120s intermittent isometric and 60s isotonic). During isometric contraction, MSOT showed a decrease of HbO

Indexed as

Hb, Deoxygenated HemoglobinHbO2, Oxygenated HemoglobinHemodynamicsMetabolic imagingMSOTMSOT, Multispectral Optoacoustic TomographyMultispectral optoacoustic tomographyMusculoskeletal physiologyMVC, Maximum Voluntary ContractionOxygenationPAD, Peripheral Arterial DiseasePhotoacousticsTBV, Total Blood Volume

Identifiers

PMID36950518
PMCPMC10025091
OpenAlexW4321769133

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read130
table measurements read5
identifiers read3
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.