Evidence mapPaperPMID 36950704Full record

ArticleRSC advances2023

Polydopamine-assisted tranilast immobilization on a PLA chamber to enhance fat flaps regeneration by reducing tissue fibrosis.

Zhangsong Peng, Qiang Chang, Xilong Liu, Danni Chen, Feng Lu, Xihang Chen

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Zhangsong PengDepartment of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University 1838 Guangzhou North Road Guangzhou Guangdong 510515 China XihangChen@hotmail.com doctorlufeng@hotmail.com +86 (020) 61641869 +86 (020) 61641869.ORCID https://orcid.org/0000-0002-8243-6435
Qiang ChangDepartment of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University 1838 Guangzhou North Road Guangzhou Guangdong 510515 China XihangChen@hotmail.com doctorlufeng@hotmail.com +86 (020) 61641869 +86 (020) 61641869.ORCID https://orcid.org/0000-0002-0397-2150
Xilong LiuDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University Guangzhou China.
Danni ChenDepartment of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University 1838 Guangzhou North Road Guangzhou Guangdong 510515 China XihangChen@hotmail.com doctorlufeng@hotmail.com +86 (020) 61641869 +86 (020) 61641869.
Feng LuDepartment of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University 1838 Guangzhou North Road Guangzhou Guangdong 510515 China XihangChen@hotmail.com doctorlufeng@hotmail.com +86 (020) 61641869 +86 (020) 61641869.
Xihang ChenDepartment of Plastic and Cosmetic Surgery, Nanfang Hospital, Southern Medical University 1838 Guangzhou North Road Guangzhou Guangdong 510515 China XihangChen@hotmail.com doctorlufeng@hotmail.com +86 (020) 61641869 +86 (020) 61641869.
Nanfang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue engineering chambers (TECs) have been shown to be useful in regenerating adipose tissue. However, tissue fibrosis caused by the chambers compromises the final volume of the newly formed adipose tissue. Surface modifications can compensate for the lack of biocompatibility of an implant. Tranilast (Tra) is an antifibrotic drug used to treat fibrotic pathologies, including keloids and scleroderma. In this study, a polydopamine-assisted tranilast coating (pDA + Tra) was prepared on a polylactic acid (PLA) chamber to minimize tissue fibrosis and achieve a large volume of fat flap regeneration. The

Identifiers

PMID36950704
PMCPMC10025940
OpenAlexW4328023037

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.