Evidence map›Paper›PMID 36952432›Full record

ArticlePloS one2023

Exploring the growth trait molecular markers in two sheep breeds based on Genome-wide association analysis.

Mirenisa Tuersuntuoheti, Jihu Zhang, Wen Zhou, Cheng-Long Zhang, Chunjie Liu, Qianqian Chang, Shudong Liu

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Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Candidate genes related to growth and milk production in three Anatolian goats revealed by GWAS.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Association Analysis of SNPs inAnimals : an open access journal from MDPI · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Animals : an open access journal from MDPI · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mirenisa TuersuntuohetiCollege of Animal Science and Technology, Tarim University, Alar, China.
Jihu ZhangCollege of Animal Science and Technology, Tarim University, Alar, China.ORCID 0000-0002-2802-8588
Wen ZhouCollege of Animal Science and Technology, Tarim University, Alar, China.
Cheng-Long ZhangCollege of Animal Science and Technology, Tarim University, Alar, China.
Chunjie LiuCollege of Animal Science and Technology, Tarim University, Alar, China.
Qianqian ChangCollege of Animal Science and Technology, Tarim University, Alar, China.
Shudong LiuCollege of Animal Science and Technology, Tarim University, Alar, China.ORCID 0000-0003-4602-8570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth traits are quantitative traits controlled by multiple micro-effect genes. we identified molecular markers related to sheep growth traits, which formed the basis of molecular breeding. In this study, we randomly selected 100 Qira Black sheep and 84 German Merino sheep for the blood collection the jugular vein to genotype by using the Illumina Ovine SNP 50K Bead Chip. quality control criteria for statistical analysis were: rejection detection rate < 90% and minimum allele frequency (MAF) < 5%. Then, we performed Genome-wide association studies (GWAS) on sheep body weight, body height, body length, and chest circumference using mixed linear models. After getting 55 SNPs with significant correlation, they were annotated by reference genome of Ovis aries genome (Oar_v4.0) and We obtained a total of 84 candidate genes associated with production traits (BMPR1B, HSD17B3, TMEM63C, etc.). We selected BMPR1B for population validation and found a correlation between the FecB locus and body weight traits. Therefore, this study not only supplements the existing knowledge of molecular markers of sheep growth traits, but also has important theoretical significance and reference value for the mining of functional genes of sheep growth traits.

Indexed as

GenomeGenome-Wide Association StudyAnimalsBody WeightGenotypePhenotypePolymorphism, Single NucleotideSheepSheep, Domestic

Identifiers

PMID36952432
PMCPMC10035858

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read25
identifiers read12
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.