Evidence map›Paper›PMID 36960521›Full record

ReviewIndian journal of pharmacology

Peptides and peptidomimetics as a therapeutic candidate for the treatment of COVID-19: A brief review.

J Kumaravel, Harvinder Singh, Sukhmeet Kaur, Ajay Prakash, Bikash Medhi

Open access · greenAbstract readReview
In one paragraph

Review in Indian journal of pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J KumaravelDepartment of Pharmacology, PGIMER, Chandigarh, India.
Harvinder SinghDepartment of Pharmacology, PGIMER, Chandigarh, India.
Sukhmeet KaurDepartment of Pharmacology, PGIMER, Chandigarh, India.
Ajay PrakashDepartment of Pharmacology, PGIMER, Chandigarh, India.
Bikash MedhiDepartment of Pharmacology, PGIMER, Chandigarh, India.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel SARS-CoV-2 (COVID-19) is affecting worldwide as declared pandemic by the WHO. Various repositioning and novel therapeutic agents are being evaluated under different clinical setups; however, there is no promising therapeutic agent reported to date. Small molecules like peptides have their popularity as their specificity, delivery, and synthesizability as promising therapeutic agents. In this study, we have reviewed the published literature describing peptide designing, in silico binding mode, antiviral activity, preventive measures, and in vivo assessments. Here, we reported all the results which are promising against SARS-CoV-2 as therapeutic and preventive (vaccine candidates), and their status in the drug development process.

Indexed as

COVID-19PeptidomimeticsAntiviral AgentsDrug RepositioningHumansPeptidesSARS-CoV-2Antiviral AgentsPeptidesPeptidomimeticsCOVID-19peptidespeptidomimetics

Identifiers

PMID36960521
PMCPMC10204890
OpenAlexW4360804457

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.