Evidence map›Paper›PMID 36967707›Full record

ArticleJournal of cellular and molecular medicine2023

Differential changes in cyclic adenosine 3'-5' monophosphate (cAMP) effectors and major Ca

Victoria Chaoul, Rita Hanna, Pia Hachem, Magali Samia El Hayek, Wared Nour-Eldine, Pamela Abou-Khalil, Elias Abi-Ramia, Grégoire Vandecasteele, Aniella Abi-Gerges

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Victoria ChaoulGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Rita HannaGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Pia HachemGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Magali Samia El HayekSignaling and Cardiovascular Pathophysiology, UMR-S1180, Université Paris-Saclay, Orsay, 91400, France.
Wared Nour-EldineGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.ORCID 0000-0002-7605-6989
Pamela Abou-KhalilGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Elias Abi-RamiaSchool of Arts and Sciences, Department of Natural Sciences, Lebanese American University, Byblos, Lebanon.
Grégoire VandecasteeleSignaling and Cardiovascular Pathophysiology, UMR-S1180, Université Paris-Saclay, Orsay, 91400, France.ORCID 0000-0002-4046-4171
Aniella Abi-GergesGilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, P.O. Box 36, Byblos, Lebanon.ORCID 0000-0001-9974-4023
Lebanese American University · LBUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic cardiomyopathy (DCM) is associated with differential and time-specific regulation of β-adrenergic receptors and cardiac cyclic nucleotide phosphodiesterases with consequences for total cyclic adenosine 3'-5' monophosphate (cAMP) levels. We aimed to investigate whether these changes are associated with downstream impairments in cAMP and Ca

Indexed as

Diabetes Mellitus, Type 1Diabetic CardiomyopathiesAdenosineAnimalsCalcium-Binding ProteinsCalcium-Calmodulin-Dependent Protein Kinase Type 2MaleMyocardiumPhosphorylationRatsSerineTroponin IAdenosineCalcium-Binding ProteinsCalcium-Calmodulin-Dependent Protein Kinase Type 2SerineTroponin ICa2+/calmodulin-dependent kinase IIcAMP-dependent protein kinasediabetic cardiomyopathyexchange protein directly activated by cAMPexcitation-contraction couplingtype 1 diabetes

Identifiers

PMID36967707
PMCPMC10148055
OpenAlexW4361010119

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.