Evidence map›Paper›PMID 36968754›Full record

ArticleFrontiers in psychology2023

Improving adherence to immunosuppression after liver or kidney transplantation in individuals with impairments in personality functioning - A randomized controlled single center feasibility study.

Jolana Wagner-Skacel, Nadja Fink, Judith Kahn, Nina Dalkner, Emanuel Jauk, Susanne Bengesser, Marco Mairinger, Gerhard Schüssler, Christoph Pieh, Vanessa Stadlbauer and 5 more

Registry-linked trialOpen access · goldFull text read
In one paragraph

Article in Frontiers in psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04207125 (Improving ImmunoSuppression Adherence After Liver or Kidney Transplantation -a Randomized Controlled Single Centre Trial), which is not on this map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04207125 naunknown statusnot on this map

Improving ImmunoSuppression Adherence After Liver or Kidney Transplantation -a Randomized Controlled Single Centre Trial

TypeinterventionalSponsorMedical University of GrazRan2020 to 2021Enrolled150ConditionsAdherence Intervention Post TransplantationArmsMultilevel psychotherapeutic intervention programme
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Jolana Wagner-SkacelDepartment of Medical Psychology, Psychosomatics, and Psychotherapy, Medical University of Graz, Graz, Austria.
Nadja FinkUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Judith KahnUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Nina DalknerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
Emanuel JaukDepartment of Medical Psychology, Psychosomatics, and Psychotherapy, Medical University of Graz, Graz, Austria.
Susanne BengesserDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
Marco MairingerDepartment of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.
Gerhard SchüsslerDepartment of Medical Psychology, Psychosomatics, and Psychotherapy, Medical University of Graz, Graz, Austria.
Christoph PiehDepartment of Psychosomatic Medicine, University for Continuing Education Krems, Krems an der Donau, Austria.
Vanessa StadlbauerDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Alexander H KirschUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Sabine ZittaUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Alexander R RosenkranzUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Peter FickertUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Peter SchemmerUniversity Transplant Center Graz, Medical University of Graz, Graz, Austria.
Medical University of Graz · ATUniversität für Weiterbildung Krems · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Although adherence to immunosuppressive medication is the key factor for long-term graft survival today, 20-70% of transplant recipients are non-adherent to their immunosuppressive medication. Objective: A prospective, randomized, controlled single-center feasibility study was designed to evaluate the impact of a step guided multicomponent interprofessional intervention program for patients after kidney or liver transplantation on adherence to their immunosuppressive medication in daily clinical practice. Materials and methods: The intervention consisted of group therapy and daily training as well as individual sessions in a step guided approach. The primary endpoint of the study was adherence to immunosuppression as assessed with the "Basel Assessment of Adherence to Immunosuppressive Medications Scale" (BAASIS). The coefficient of variation (CV%) of Tacrolimus (TAC) through levels and the level of personality functioning was a secondary endpoint. We conducted six monthly follow-up visits. Results: Forty-one age- and sex-matched patients [19 females, 58.5 ( Discussion: The results of the feasibility study showed that this intervention program was highly accepted in the clinical setting. The Intervention group could compensate higher CV% of TAC after liver or kidney transplantation in individuals with lower levels of personality functioning and non-adherence. Clinical trial registration: ClinicalTrials.gov, identifier NCT04207125.

Indexed as

adherenceimmunosuppressionkidney transplantationliver transplantationmultilevel intervention

Identifiers

PMID36968754
PMCPMC10033957
OpenAlexW4323665968

What Socratic holds

Textfull text, public
LicenceCC BY
reference markers read4
measurements read12
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.