Evidence mapPaperPMID 36970140Full record

ArticleRSC medicinal chemistry2023

Quinazolinone-1,2,3-triazole-acetamide conjugates as potent α-glucosidase inhibitors: synthesis, enzyme inhibition, kinetic analysis, and molecular docking study.

Sara Moghadam Farid, Aida Iraji, Somayeh Mojtabavi, Mehrnaz Ghasemi, Mohammad Ali Faramarzi, Mohammad Mahdavi, Maliheh Barazandeh Tehrani, Tahmineh Akbarzadeh, Mina Saeedi

Abstract read
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Article in RSC medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sara Moghadam FaridEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran.
Aida IrajiStem Cells Technology Research Center, Shiraz University of Medical Sciences Shiraz Iran.
Somayeh MojtabaviDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences P.O. Box 14155-6451 Tehran 1417614411 Iran.
Mehrnaz GhasemiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences Tehran Iran barazand@tums.ac.ir.
Mohammad Ali FaramarziDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences P.O. Box 14155-6451 Tehran 1417614411 Iran.ORCID https://orcid.org/0000-0002-8822-453X
Mohammad MahdaviEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran.
Maliheh Barazandeh TehraniDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences Tehran Iran barazand@tums.ac.ir.
Tahmineh AkbarzadehDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences Tehran Iran barazand@tums.ac.ir.
Mina SaeediPersian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences Tehran Iran m-saeedi@tums.ac.ir.ORCID https://orcid.org/0000-0002-4053-6331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, new hybrids of quinazolinone-1,2,3-triazole-acetamide were designed, synthesized, and screened for their α-glucosidase inhibitory activity. The results obtained from the

Identifiers

PMID36970140
PMCPMC10033893

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.