Evidence map›Paper›PMID 36970280›Full record

ArticleFrontiers in psychiatry2023

Striatal increase of dopamine receptor 2 density in idiopathic and syndromic mouse models of autism spectrum disorder.

Stuti Chhabra, Leonardo Nardi, Petra Leukel, Clemens J Sommer, Michael J Schmeisser

Open access · goldFull text read
In one paragraph

Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Subcortical dopamine DEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stuti ChhabraInstitute of Anatomy, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.
Leonardo NardiInstitute of Anatomy, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.
Petra LeukelInstitute of Neuropathology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.
Clemens J SommerFocus Program Translational Neurosciences, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.
Michael J SchmeisserInstitute of Anatomy, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.
University Medical Center of the Johannes Gutenberg University Mainz · DEFocus (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) comprises a wide range of neurodevelopmental phenotypes united by impaired social interaction and repetitive behavior. Environmental and genetic factors are associated with the pathogenesis of ASD, while other cases are classified as idiopathic. The dopaminergic system has a profound impact in the modulation of motor and reward-motivated behaviors, and defects in dopaminergic circuits are implicated in ASD. In our study, we compare three well-established mouse models of ASD, one idiopathic, the BTBR strain, and two syndromic,

Indexed as

ASDautism (ASD)dopamine receptor (d1r and d2r)dorsal striatumreceptor autoradiographyventral striatum

Identifiers

PMID36970280
PMCPMC10030619
OpenAlexW4323567116

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read19
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.