Evidence map›Paper›PMID 36970659›Full record

ArticleFrontiers in neuroinformatics2023

A neuroscientist's guide to using murine brain atlases for efficient analysis and transparent reporting.

Heidi Kleven, Ingrid Reiten, Camilla H Blixhavn, Ulrike Schlegel, Martin Øvsthus, Eszter A Papp, Maja A Puchades, Jan G Bjaalie, Trygve B Leergaard, Ingvild E Bjerke

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Article in Frontiers in neuroinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Developmental Mouse Brain Common Coordinate Framework.bioRxiv : the preprint server for biology · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Heidi KlevenNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Ingrid ReitenNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Camilla H BlixhavnNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Ulrike SchlegelNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Martin ØvsthusNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Eszter A PappNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Maja A PuchadesNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Jan G BjaalieNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Trygve B LeergaardNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Ingvild E BjerkeNeural Systems Laboratory, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain atlases are widely used in neuroscience as resources for conducting experimental studies, and for integrating, analyzing, and reporting data from animal models. A variety of atlases are available, and it may be challenging to find the optimal atlas for a given purpose and to perform efficient atlas-based data analyses. Comparing findings reported using different atlases is also not trivial, and represents a barrier to reproducible science. With this perspective article, we provide a guide to how mouse and rat brain atlases can be used for analyzing and reporting data in accordance with the FAIR principles that advocate for data to be findable, accessible, interoperable, and re-usable. We first introduce how atlases can be interpreted and used for navigating to brain locations, before discussing how they can be used for different analytic purposes, including spatial registration and data visualization. We provide guidance on how neuroscientists can compare data mapped to different atlases and ensure transparent reporting of findings. Finally, we summarize key considerations when choosing an atlas and give an outlook on the relevance of increased uptake of atlas-based tools and workflows for FAIR data sharing.

Indexed as

brain atlasesbrain-wide analysisFAIR datamouse brainneuroinformaticsrat brainreporting practicesspatial registration

Identifiers

PMID36970659
PMCPMC10033636

What Socratic holds

Textfull text, public
LicenceCC BY
reference markers read13
measurements read8
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.