Evidence map›Paper›PMID 36971091›Full record

ReviewAdvanced healthcare materials2023

Recent Advances in Organ-on-Chips Integrated with Bioprinting Technologies for Drug Screening.

Nima Tabatabaei Rezaei, Hitendra Kumar, Hongqun Liu, Samuel S Lee, Simon S Park, Keekyoung Kim

Abstract readReview
In one paragraph

Review in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Microengineered Gradient Hydrogels for Mechanobiology.Advanced healthcare materials · 2026
    Review
  6. Exploring endometriosis through 3DMaterials today. Bio · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nima Tabatabaei RezaeiDepartment of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.ORCID 0000-0002-4172-1408
Hitendra KumarDepartment of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.ORCID 0000-0003-3185-8440
Hongqun LiuLiver Unit, Cumming School of Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.
Samuel S LeeLiver Unit, Cumming School of Medicine, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.
Simon S ParkDepartment of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.
Keekyoung KimDepartment of Mechanical and Manufacturing Engineering, University of Calgary, Calgary, Alberta, T2N 1N4, Canada.ORCID 0000-0002-7442-7117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, the demand for more reliable drug screening devices has made scientists and researchers develop novel potential approaches to offer an alternative to animal studies. Organ-on-chips are newly emerged platforms for drug screening and disease metabolism investigation. These microfluidic devices attempt to recapitulate the physiological and biological properties of different organs and tissues using human-derived cells. Recently, the synergistic combination of additive manufacturing and microfluidics has shown a promising impact on improving a wide array of biological models. In this review, different methods are classified using bioprinting to achieve the relevant biomimetic models in organ-on-chips, boosting the efficiency of these devices to produce more reliable data for drug investigations. In addition to the tissue models, the influence of additive manufacturing on microfluidic chip fabrication is discussed, and their biomedical applications are reviewed.

Indexed as

BioprintingAnimalsBiomimeticsDrug Evaluation, PreclinicalHumansLab-On-A-Chip DevicesMicrofluidics3D bioprintingbiofabricationdrug screeningmicrofluidicsorgan-on-chips (OOCs)

Identifiers

PMID36971091
PMCPMC11469032

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.