Evidence map›Paper›PMID 36972762›Full record

ArticleIndian heart journal

Ultra-thin everolimus-eluting stents in atherosclerotic lesions: Three years follow-up with subgroup analysis of ultra-long stents.

Raghava Sarma Polavarapu, Vijaya Pamidimukkala, Anurag Polavarapu, Yudhistar Siripuram, Keerthika Chowdary Ravella, Murali Babu Rao Rachaputi, Naren Polavarapu, Kalyan Chakravarthi Pulivarthi, Sravanthi Byrapaneni, Sirichandana Gangasani and 2 more

Open access · goldAbstract read
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Raghava Sarma PolavarapuDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: drpvraghav@gmail.com.
Vijaya PamidimukkalaDepartment of Neurosciences, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: drvijayapvr@gmail.com.
Anurag PolavarapuDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: anurag.polavarapu@gmail.com.
Yudhistar SiripuramDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: yudhistar1987@gmail.com.
Keerthika Chowdary RavellaDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: ravellamk@gmail.com.
Murali Babu Rao RachaputiDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: mrachaputi@hotmail.com.
Naren PolavarapuDepartment of General Medicine, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: narenpvr12@gmail.com.
Kalyan Chakravarthi PulivarthiDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: kcpulivarthi@gmail.com.
Sravanthi ByrapaneniDepartment of Oncology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: sravanthi.byrapaneni@gmail.com.
Sirichandana GangasaniDepartment of General Medicine, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: sirichandana2886@gmail.com.
Michael NoronhaDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: nfilsana@gmail.com.
Srinivasa Rao ChintaDepartment of Cardiology, Lalitha Super Specialities Hospital, Guntur, Andhra Pradesh, India. Electronic address: srinivaspadmarao@gmail.com.
Andhra Pradesh Forest Department · INMax Super Speciality Hospital · INOrthopedic Specialty Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the long-term (3 years) safety and efficacy of Tetrilimus everolimus-eluting stent (EES) and subgroup analysis of outcomes of ultra-long (44/48 mm) Tetrilimus EES implantation in patients with long coronary lesions. MATERIAL AND

methodsIn this observational, single-centre, single-arm, investigator-initiated registry, 558 patients who underwent implantation of Tetrilimus EES for the treatment of coronary artery disease were retrospectively included. The primary endpoint was occurrence of any major adverse cardiac event (MACE) at 12 months follow-up (composite of cardiac death, myocardial infarction [MI], and target lesion revascularization [TLR]) and we hereby report 3 years follow-up data. Stent thrombosis was assessed as a safety endpoint. A subgroup analysis of patients with long coronary lesions is also reported.

resultsA total of 558 patients (57.0 ± 10.2 years) received 766 Tetrilimus EES (1.3 ± 0.5 stents/patient) to treat 695 coronary lesions. In subgroup analysis of 143 patients implanted with ultra-long EES, 155 lesions were intervened successfully with only one Tetrilimus EES (44/48 mm) implanted per lesion. At 3 years, event rates of 9.1% MACE with predominance of MI (4.4%), followed by 2.9% TLR and 1.7% cardiac death, and only 1.0% stent thrombosis were reported in overall population, while in a subgroup of patients implanted with ultra-long EES, 10.4% MACE and 1.5% stent thrombosis were reported.

conclusionsThree years clinical outcomes showed favourable long-term safety and excellent performance of Tetrilimus EES in high-risk patients and complex coronary lesions in routine clinical practice, including a subgroup of patients with long coronary lesions, with acceptable primary and safety endpoints.

Indexed as

AtherosclerosisCoronary ThrombosisDrug-Eluting StentsMyocardial InfarctionPercutaneous Coronary InterventionDeathEverolimusFollow-Up StudiesHumansProsthesis DesignRetrospective StudiesRisk FactorsStentsTreatment OutcomeEverolimusBiodegradable polymerDrug-eluting stentsEverolimusPercutaneous coronary intervention

Identifiers

PMID36972762
PMCPMC10421990
OpenAlexW4360838346

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.