Evidence map›Paper›PMID 36972981›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2023

Effects of Controlled Supramaximal High-Intensity Interval Training on Cardiorespiratory Fitness and Global Cognitive Function in Older Adults: The Umeå HIT Study-A Randomized Controlled Trial.

Emma Simonsson, Sofi Levik Sandström, Mattias Hedlund, Henrik Holmberg, Bengt Johansson, Nina Lindelöf, Carl-Johan Boraxbekk, Erik Rosendahl

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03765385 (The Umeå High-Intensity Training Study), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03765385 nacompletednot on this map

The Umeå High-Intensity Training Study: Feasibility and Effect of High-Intensity Training in Older Sedentary People

TypeinterventionalSponsorUmeå UniversityRan2018 to 2020Enrolled68ConditionsAgedArmsHigh-intensity training, Moderate-intensity continuous training
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  9. Article
  10. High intensity interval training for older adults - from the laboratory towards a home setting: a co-creation study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Article
  11. Article
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  14. Cardiovascular load and physical capacity in older workers engaged in physically demanding occupations.International archives of occupational and environmental health · 2025
    Article
  15. Supramaximal high-intensity interval training for older adults in a community setting: a pragmatic feasibility study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Emma SimonssonDepartment of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden.ORCID 0000-0002-5625-315X
Sofi Levik SandströmDepartment of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.
Mattias HedlundDepartment of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden.
Henrik HolmbergDepartment of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Bengt JohanssonDepartment of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.ORCID 0000-0003-0976-6910
Nina LindelöfDepartment of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden.
Carl-Johan BoraxbekkDepartment of Radiation Sciences, Diagnostic Radiology, Umeå University, Umeå, Sweden.
Erik RosendahlDepartment of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Umeå, Sweden.
Umeå University · SEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study examined the effects of regulated and controlled supramaximal high-intensity interval training (HIT) adapted for older adults, compared to moderate-intensity training (MIT), on cardiorespiratory fitness; cognitive, cardiovascular, and muscular function; and quality of life.

methodsSixty-eight nonexercising older adults (66-79 years, 44% males) were randomized to 3 months of twice-weekly HIT (20-minute session including 10 × 6-second intervals) or MIT (40-minute session including 3 × 8-minute intervals) on stationary bicycles in an ordinary gym setting. Individualized target intensity was watt controlled with a standardized pedaling cadence and individual adjustment of the resistance load. Primary outcomes were cardiorespiratory fitness (V̇o2peak) and global cognitive function (unit-weighted composite).

resultsV̇o2peak increased significantly (mean 1.38 mL/kg/min, 95% CI [0.77, 1.98]), with no between-group difference (mean difference 0.05 [-1.17, 1.25]). Global cognition did not improve (0.02 [-0.05, 0.09]), nor differed between groups (0.11 [-0.03, 0.24]). Significant between-group differences in change were observed for working memory (0.32 [0.01, 0.64]), and maximal isometric knee extensor muscle strength (0.07 N·m/kg [0.003, 0.137]), both in favor of HIT. Irrespective of the group, there was a negative change in episodic memory (-0.15 [-0.28, -0.02]), a positive change in visuospatial ability (0.26 [0.08, 0.44]), and a decrease in systolic (-2.09 mmHg [-3.54, -0.64]) and diastolic (-1.27 mmHg [-2.31, -0.25]) blood pressure.

conclusionsIn nonexercising older adults, 3 months of watt-controlled supramaximal HIT improved cardiorespiratory fitness and cardiovascular function to a similar extent as MIT, despite half the training time. In favor of HIT, there was an improvement in muscular function and a potential domain-specific effect on working memory. CLINICAL

trial registrationNCT03765385.

Indexed as

Cardiorespiratory FitnessHigh-Intensity Interval TrainingAgedCognitionFemaleHumansMaleQuality of LifeAerobic capacityHIITModerate-intensity trainingSITSprint interval training

Identifiers

PMID36972981
PMCPMC10460559
OpenAlexW4361190695

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.