Evidence map›Paper›PMID 36973009›Full record

ArticleeNeuro2023

Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types.

Meaghan E McCoy, Anna K Kamitakahara

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Glucagon-Like Peptide-1 Targets in the Human Nodose Ganglion.The Journal of comparative neurology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Meaghan E McCoyThe Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California 90027.ORCID 0000-0002-3783-3503
Anna K KamitakaharaThe Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California 90027 kamitaka@usc.edu.ORCID 0000-0001-7213-4145
Children's Hospital of Los Angeles · USUniversity of Southern California · US

Funding

Leptin and the Nutritional Programming of Obesity and DiabetesR01DK084142 · NIDDK · CHILDREN'S HOSPITAL OF LOS ANGELES · PI LEVITT, PAT · 2010 to 2022
$4.3M
Impact of Early Life Experience on Vagal Neurons and CircuitsR01DK126085 · NIDDK · CHILDREN'S HOSPITAL OF LOS ANGELES · PI LEVITT, PAT, RINAMAN, LINDA M · 2021 to 2024
$2.9M
NIDDK NIH HHS R01 DK084142NIDDK NIH HHS R01 DK126085
6 · The paper itself

Abstract

Vagal sensory neurons (VSNs) located in the nodose ganglion provide information, such as stomach stretch or the presence of ingested nutrients, to the caudal medulla via specialized cell types expressing unique marker genes. Here, we leverage VSN marker genes identified in adult mice to determine when specialized vagal subtypes arise developmentally and the trophic factors that shape their growth. Experiments to screen for trophic factor sensitivity revealed that brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) robustly stimulate neurite outgrowth from VSNs

Indexed as

Brain-Derived Neurotrophic FactorGlial Cell Line-Derived Neurotrophic FactorAnimalsFemaleGastrointestinal TractMaleMiceSensory Receptor CellsVagus NerveBrain-Derived Neurotrophic FactorGlial Cell Line-Derived Neurotrophic Factorcell typedevelopmentneurotrophic factornodose gangliavagus

Identifiers

PMID36973009
PMCPMC10124152
OpenAlexW4361018513

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.