Evidence map›Paper›PMID 36973452›Full record

ArticleNeuroradiology2023

Recurrent reversible in-stent-stenosis after flow diverter treatment.

Malvina Garner, Frederik Fries, Alena Haußmann, Michael Kettner, Armin Bachhuber, Wolfgang Reith, Umut Yilmaz

Registry-linked trialOpen access · hybridAbstract readCase Reports
In one paragraph

Article in Neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07420179 (Derivo-ISS), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07420179 nacompletednot on this map

Derivo-ISS: A Prospective Randomized Study Comparing In-Stent Stenosis After Treatment With a Coated Versus Uncoated Flow Diverter (Derivo 2 Heal vs Derivo 2) for Intracranial ICA Aneurysms

TypeinterventionalSponsorUniversität des SaarlandesRan2021 to 2025Enrolled21ConditionsAneurysm CerebralArmsCoated Flow Diverter, Uncoated Flow Diverter
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Malvina GarnerDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany.
Frederik FriesDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany.
Alena HaußmannDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany.
Michael KettnerDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany.
Armin BachhuberDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany.
Wolfgang ReithDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany.
Umut YilmazDepartment of Neuroradiology, Saarland University Hospital, Kirrberger Str, D-66424, Homburg, Germany. umut.yilmaz@uks.eu.ORCID http://orcid.org/0000-0003-4940-3575
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flow diverter stents (FDS) are well established in the treatment of intracranial aneurysms which are difficult to treat with conventional endovascular techniques. However, they carry a relatively high risk of specific complications compared to conventional stents. A minor but frequent finding is the occurrence of reversible in-stent-stenosis (ISS) that tend to resolve spontaneously over time. Here, we report the case of a patient in their 30s who was treated with FDS for bilateral paraophthalmic internal carotid artery (ICA) aneurysms. ISS were found at the respective early follow-up examinations on both sides and had resolved at the 1-year follow-up examinations. Surprisingly ISS reoccurred at both sides in later follow-up examinations and again resolved spontaneously. The recurrence of ISS after resolution is a finding that has not been described previously. Its incidence and further development should be investigated systematically. This might contribute to our understanding of the mechanisms underlying the effect of FDS.

Indexed as

Carotid Artery DiseasesEmbolization, TherapeuticEndovascular ProceduresIntracranial AneurysmCerebral AngiographyConstriction, PathologicHumansRetrospective StudiesStentsTreatment OutcomeFlow diverter stentIn-stent-stenosisIntracranial aneurysm

Identifiers

PMID36973452
PMCPMC10272252
OpenAlexW4361190663

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.