Evidence map›Paper›PMID 36973489›Full record

ArticleCellular & molecular immunology2023

A T follicular helper cell origin for T regulatory type 1 cells.

Patricia Solé, Jun Yamanouchi, Josep Garnica, Muhammad Myn Uddin, Robert Clarke, Joel Moro, Nahir Garabatos, Shari Thiessen, Mireia Ortega, Santiswarup Singha and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Antigen-specific immunotherapy with a CD4Nature communications · 2026
    Article
  6. Article
  7. Article
  8. Resolving ScRNA-Seq Signatures of Antigen-Specific CD4bioRxiv : the preprint server for biology · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Patricia SoléInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Jun YamanouchiDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Josep GarnicaInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.ORCID http://orcid.org/0000-0001-9493-1321
Muhammad Myn UddinDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Robert ClarkeDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Joel MoroInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Nahir GarabatosInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Shari ThiessenDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Mireia OrtegaInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Santiswarup SinghaDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Debajyoti MondalDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
César FandosInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Julio Saez-RodriguezInstitute of Computational Biomedicine, Faculty of Medicine, Heidelberg University, Heidelberg, Germany.
Yang YangDepartment of Microbiology, Immunology and Infectious Diseases, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Pau SerraInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
Pere SantamariaInstitut D'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain. psantama@ucalgary.ca.ORCID http://orcid.org/0000-0003-3469-1586
University of Calgary · CAConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic antigenic stimulation can trigger the differentiation of antigen-experienced CD4

Indexed as

T Follicular Helper CellsT-Lymphocytes, Helper-InducerAntigensCell DifferentiationGene Expression RegulationGerminal CenterHistocompatibility Antigens Class IIT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsAntigensHistocompatibility Antigens Class IIautoimmunitynanomedicineT follicular helper (TFH) cellstransdifferentiationT-regulatory type 1 (TR1) cells

Identifiers

PMID36973489
PMCPMC10202951
OpenAlexW4361007123

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.