Evidence map›Paper›PMID 36974476›Full record

ReviewAnnals of medicine2023

The melatonin receptor 1B gene links circadian rhythms and type 2 diabetes mellitus: an evolutionary story.

Hui Zhu, Zhi-Jia Zhao, Hong-Yi Liu, Jie Cai, Qin-Kang Lu, Lin-Dan Ji, Jin Xu

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hui ZhuDepartment of Internal Medicine, Health Science Center, Ningbo University, Ningbo, Zhejiang, P. R. China.ORCID 0000-0002-3159-8549
Zhi-Jia ZhaoSchool of Public Health, Health Science Center, Ningbo University, Ningbo, Zhejiang, P. R. China.
Hong-Yi LiuSchool of Public Health, Health Science Center, Ningbo University, Ningbo, Zhejiang, P. R. China.
Jie CaiCenter for Reproductive Medicine, Ningbo Women and Children's Hospital, Ningbo, Zhejiang, P. R. China.
Qin-Kang LuDepartment of Ophthalmology, Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang, P. R. China.
Lin-Dan JiDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Health Science Center, Ningbo, Zhejiang, P. R. China.
Jin XuSchool of Public Health, Health Science Center, Ningbo University, Ningbo, Zhejiang, P. R. China.
Ningbo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disturbed circadian rhythms have been a risk factor for type 2 diabetes mellitus (T2DM). Melatonin is the major chronobiotic hormone regulating both circadian rhythm and glucose homeostasis. The rs10830963 (G allele) of the

Indexed as

Circadian RhythmDiabetes Mellitus, Type 2MelatoninReceptor, Melatonin, MT2Blood GlucoseGenome-Wide Association StudyHumansPolymorphism, Single NucleotideBlood GlucoseMelatoninMTNR1B protein, humanReceptor, Melatonin, MT2MelatoninMTNR1Bthrifty geneType 2 diabetes mellitus

Identifiers

PMID36974476
PMCPMC10054309
OpenAlexW4361208088

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.