Evidence mapPaperPMID 36974507Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Body Composition Changes Over the Menopausal Transition in Women With and Without Human Immunodeficiency Virus.

Rebecca A Abelman, Thuy Trang J Nguyen, Yifei Ma, Peter Bacchetti, Geralyn Messerlian, Audrey L French, Anjali Sharma, Howard Minkoff, Michael Plankey, Carl Grunfeld and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Switch to Integrase Strand Transfer Inhibitors During the Menopausal Transition Is Associated With Accelerated Body Composition Change in Women With HIV.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Rebecca A AbelmanDepartment of Medicine, University of California, San Francisco, USA.
Thuy Trang J NguyenDepartment of Medicine, University of California, San Francisco, USA.
Yifei MaDepartment of Medicine, University of California, San Francisco, USA.
Peter BacchettiDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Geralyn MesserlianDepartment of Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.
Audrey L FrenchDepartment of Medicine, Stroger Hospital, Cook County Health, Chicago, Illinois, USA.
Anjali SharmaDepartment of Medicine, Albert Einstein College of Medicine, New York, USA.
Howard MinkoffDepartment of Obstetrics and Gynecology, State University of New York Downstate Health Sciences University, Brooklyn, USA.
Michael PlankeyDepartment of Medicine, Georgetown University Medical Center, Washington, District of Columbia, USA.ORCID 0000-0003-4554-7483
Carl GrunfeldDepartment of Medicine, University of California, San Francisco, USA.
Phyllis C TienDepartment of Medicine, University of California, San Francisco, USA.
University of California, San Francisco · USSan Francisco VA Medical Center · USAlbert Einstein College of Medicine · USBrown University · USGeorgetown University · USJohn H. Stroger, Jr. Hospital of Cook County · USState University of New York · US

Funding

UAB Center for AIDS Research (CFAR)P30AI027767 · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 1988 to 2025
$12.1M
Infant Immunization to Reduce Pneumonia in HIV +ve womenP30AI050409 · EMORY UNIVERSITY · 2002 to 2025
$11.1M
UNC Center for AIDS Research Core F BiostatisticsP30AI050410 · UNIV OF NORTH CAROLINA CHAPEL HILL · 2001 to 2025
$10.9M
UCLA Clinical and Translational Science InstituteUL1TR001881 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2025 to 2025
$9.9M
Clinical and Translational Science InstituteUL1TR001872 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2025 to 2025
$8.5M
UCSF Liver CenterP30DK026743 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 1986 to 2025
$6.5M
Data Analysis and Coordination Center for the MACS-WIHS Combined Cohort StudyU01HL146193 · JOHNS HOPKINS UNIVERSITY · 2025 to 2025
$4.8M
SF Bay Area MACS/WIHS Combined Cohort StudyU01HL146242 · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2025 to 2025
$4.4M
Los Angeles CRS for the MACS/WIHS Combined Cohort StudyU01HL146333 · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2025 to 2025
$4.3M
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS)U01HL146204 · ALBERT EINSTEIN COLLEGE OF MEDICINE · 2025 to 2025
$4.1M
University of Pittsburgh MACS/WIHS CCSU01HL146208 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2025 to 2025
$4.0M
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC CenterU01HL146201 · JOHNS HOPKINS UNIVERSITY · 2025 to 2025
$4.0M
NCATS NIH HHS UL1 TR000004NCATS NIH HHS UL1 TR001872NCATS NIH HHS UL1 TR001881NCATS NIH HHS UL1 TR003098NHLBI NIH HHS U01 HL146192NHLBI NIH HHS U01 HL146193NHLBI NIH HHS U01 HL146194NHLBI NIH HHS U01 HL146201NHLBI NIH HHS U01 HL146202NHLBI NIH HHS U01 HL146203NHLBI NIH HHS U01 HL146204NHLBI NIH HHS U01 HL146208NHLBI NIH HHS U01 HL146240NHLBI NIH HHS U01 HL146241NHLBI NIH HHS U01 HL146242NHLBI NIH HHS U01 HL146245NHLBI NIH HHS U01 HL146333NIAID NIH HHS K24 AI108516NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI050410NIAID NIH HHS P30 AI073961NIAID NIH HHS T32 AI060530NIDDK NIH HHS P30 DK026743NIDDK NIH HHS R01 DK109823NIMH NIH HHS P30 MH116867
6 · The paper itself

Abstract

backgroundWomen are at risk for weight gain during the transition to menopause, but few have examined the contribution of menopause to weight gain in women with human immunodeficiency virus (WWH).

methodsFrom 2000 to 2013, participants (621 WWH; 218 without HIV [WWOH]) from the Women's Interagency HIV Study were categorized by menopausal phase using serial measures of anti-Müllerian hormone (AMH). Multivariable linear mixed models examined the association of menopausal phase with body mass index (BMI) and waist circumference (WC) trajectory, stratified by HIV status.

resultsIn models controlled for chronologic age, the estimated effects (95% confidence interval) of menopausal phase on annual rate of BMI change across early perimenopause, late perimenopause, and menopause, respectively, compared to premenopause were -0.55% (-.80 to -.30), -0.29% (-.61 to .03), and -0.67% (-1.12 to -.20) in WWH, whereas estimated effects were 0.43% (-.01 to .87) and 0.15% (-.42 to .71) across early and late perimenopause, respectively, and -0.40% (-1.24 to .45) across menopause in WWOH. The estimated effects on rate of WC change were negative across early perimenopause (-0.21% [-.44 to .03]) and menopause (-0.12% [-.5 to .26]) and positive across late perimenopause (0.18% [-.10 to .45]) in WWH, and positive across all 3 menopausal phases in WWOH, but these effects were not statistically significant.

conclusionsIn WWH, the menopausal transition was associated with BMI and WC trajectories that were mostly in a negative direction and opposite from WWOH after adjusting for age, suggesting that HIV blunts weight gain during the menopausal transition.

Indexed as

HIVHIV InfectionsBody CompositionBody Mass IndexFemaleHumansMenopauseWeight GainBMIHIVmenopausewaist circumferenceweight gain

Identifiers

PMID36974507
PMCPMC10371311
OpenAlexW4361190344

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.