Evidence map›Paper›PMID 36975410›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Predictive Value of Inflammatory and Nutritional Indexes in the Pathology of Bladder Cancer Patients Treated with Radical Cystectomy.

Nebojsa Prijovic, Miodrag Acimovic, Veljko Santric, Branko Stankovic, Predrag Nikic, Ivan Vukovic, Ivan Soldatovic, Djordje Nale, Luka Kovacevic, Petar Nale and 2 more

Full text read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nebojsa PrijovicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.ORCID 0000-0002-5268-5801
Miodrag AcimovicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Veljko SantricClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Branko StankovicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Predrag NikicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Ivan VukovicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Ivan SoldatovicFaculty of Medicine, University of Belgrade, Dr Subotica Str. 8, 11000 Belgrade, Serbia.
Djordje NaleClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Luka KovacevicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Petar NaleClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Adrian MarinkovicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.
Uros BabicClinic of Urology, University Clinical Center of Serbia, Resavska Str. 51, 11000 Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the focus of numerous studies has been the predictive value of inflammatory and nutritional parameters in oncology patients. The aim of our study was to examine the relationship between the inflammatory and nutritional parameters and the histopathological characteristics of patients with bladder cancer. A retrospective study included 491 patients who underwent radical cystectomy for bladder cancer between 2017 and 2021. We calculated the preoperative values of the neutrophil-to-lymphocyte ratio (NLR), the derived neutrophil-to-lymphocyte ratio (dNLR), the systemic immune-inflammation index (SII), the systemic inflammatory response index (SIRI), the platelet-to-lymphocyte ratio (PLR), the lymphocyte-to-monocyte ratio (LMR), the prognostic nutritional index (PNI), and the geriatric nutritional risk index (GNRI). Statistically significant positive correlations were observed between NLR, dNLR, SII, SIRI, and PLR and the pathological stage of the tumor. We observed statistically significant inverse correlations for LMR, PNI, and GNRI with the tumor stage. SIRI was identified as an independent predictor of the presence of LVI. dNLR was identified as an independent predictor of positive surgical margins. GNRI was identified as an independent predictor of the presence of metastases in the lymph nodes. We noticed the predictive value of SIRI, dNLR, and GNRI in the pathology of bladder cancer patients.

Indexed as

Nutrition AssessmentUrinary Bladder NeoplasmsAgedCystectomyHumansInflammationPrognosisRetrospective Studiesbladder cancerderived neutrophil-to-lymphocyte ratiogeriatric nutritional risk indexinflammationnutritionpathologysystemic inflammatory response index

Identifiers

PMID36975410
PMCPMC10047817

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.