Evidence map›Paper›PMID 36975791›Full record

ReviewInfection and immunity2023

Interspecies Interactions within the Host: the Social Network of Group B

Marlyd E Mejia, Clare M Robertson, Kathryn A Patras

Open access · greenAbstract readReview
In one paragraph

Review in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Type 2 diabetes mellitus exacerbates vaginal group BbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Genome-wide analysis ofJournal of bacteriology · 2025
    Article
  5. Re-framing the importance of Group BInfection and immunity · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marlyd E MejiaDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Clare M RobertsonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Kathryn A PatrasDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-2631-8810
Baylor College of Medicine · US

Funding

The Clinical Translational Research Certificate of Added Qualification ProgramT32GM136554 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI Melissa Suter, IGNATIA B VAN DEN VEYVER · 2020 to 2026
$3.0M
Contribution of immune modulation, metabolism, and microbiota to Group B Streptococcal urinary tract infectionR01DK128053 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI PATRAS, KATY · 2021 to 2025
$2.3M
Function of the type 7 secretion system in Group B StreptococcusR21AI169231 · NIAID · UNIVERSITY OF KENTUCKY · PI KOROTKOV, KONSTANTIN V, PATRAS, KATY · 2023 to 2024
$443k
Determining the role of the vaginal microbiota in microbial and immunological resistance to vaginal pathobiont colonizationF31AI167538 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI MEJIA, MARLYD ELIZABETH · 2022 to 2024
$143k
NIAID NIH HHS AI167538NIAID NIH HHS AI169231NIAID NIH HHS F31 AI167538NIAID NIH HHS R21 AI169231NIDDK NIH HHS DK128053NIDDK NIH HHS R01 DK128053NIGMS NIH HHS GM136554NIGMS NIH HHS T32 GM136554
6 · The paper itself

Abstract

Group B Streptococcus (GBS) is a pervasive neonatal pathogen accounting for a combined half a million deaths and stillbirths annually. The most common source of fetal or neonatal GBS exposure is the maternal microbiota. GBS asymptomatically colonizes the gastrointestinal and vaginal mucosa of 1 in 5 individuals globally, although its precise role in these niches is not well understood. To prevent vertical transmission, broad-spectrum antibiotics are administered to GBS-positive mothers during labor in many countries. Although antibiotics have significantly reduced GBS early-onset neonatal disease, there are several unintended consequences, including an altered neonatal microbiota and increased risk for other microbial infections. Additionally, the incidence of late-onset GBS neonatal disease remains unaffected and has sparked an emerging hypothesis that GBS-microbe interactions in developing neonatal gut microbiota may be directly involved in this disease process. This review summarizes our current understanding of GBS interactions with other resident microbes at the mucosal surface from multiple angles, including clinical association studies, agriculture and aquaculture observations, and experimental animal model systems. We also include a comprehensive review of

Indexed as

Infant, Newborn, DiseasesPregnancy Complications, InfectiousStreptococcal InfectionsAnimalsAnti-Bacterial AgentsFemaleHumansInfant, NewbornPregnancySocial NetworkingStreptococcus agalactiaeAnti-Bacterial Agentsgroup B Streptococcusmicrobe-microbe interactionsprobioticStreptococcus agalactiaevaginal microbiota

Identifiers

PMID36975791
PMCPMC10112235
OpenAlexW4361191022

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.