ReviewJournal of cardiovascular development and disease2023
The Impact of the Blood Lipids Levels on Arterial Stiffness.
Review in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Mapping arterial stiffness metabolic biomarkers: a bibliometric analysis.Frontiers in medicine · 2025Pooled it
- Association Between Early Vascular Aging and Cardiometabolic Diseases: A Two-Year Longitudinal Study of the EVasCu Cohort.Journal of clinical medicine · 2026Article
- Aerobic capacity at age 34 predicts arterial stiffness in age 63, independent of classical and advanced lipid-related cardiovascular risk factors: a longitudinal cohort study.Scientific reports · 2026Article
- Analysis of the impact of pharmacological treatment on arterial stiffness in patients with connective tissue diseases.American heart journal plus : cardiology research and practice · 2026Review
- The CCR/WC ratio as a predictor of dyslipidemia and Its mediating effect on hypertension in middle-aged and older adults.BMC cardiovascular disorders · 2026Article
- Aortic Elasticity and Cardiac Electrophysiological Balance in Opioid Users Receiving Buprenorphine/Naloxone Maintenance Therapy.Biomedicines · 2026Article
- Age-Dependent Lipid-Cardiovascular Interplay in Patients at High and Very High Cardiovascular Risk.Journal of clinical medicine · 2026Article
- Triglyceride glucose index and modified triglyceride glucose indices are instrumental to optimize 3P medical management for postpartum cardiovascular disease.The EPMA journal · 2026Article
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- Article
- Association Between Metabolic Scores for Visceral Fat and Arterial Stiffness.Vascular health and risk management · 2026Article
- Differential effects of demographics and risk factors on the nonlinear orthotropic mechanical properties of human femoropopliteal arteries.Biomechanics and modeling in mechanobiology · 2025Article
- Impact of cardiometabolic risk factors and its management on the reversion and progression of arterial stiffness.NPJ cardiovascular health · 2025Review
- Crosstalk Between Metabolic Biomarkers and Pulse Wave Analysis in Hypertensive Patients.Biomedicines · 2025Article
- Association of the total cholesterol to high-density lipoprotein cholesterol ratio with all-cause mortality risk in the migraine population.The journal of headache and pain · 2025Article
- Decreased Serum Decorin Levels Are Correlated with Aortic Stiffness as Assessed Using Carotid-Femoral Pulse Wave Velocity in Patients with Peritoneal Dialysis.Life (Basel, Switzerland) · 2025Article
- Impact of remnant cholesterol on short-term mortality in acute decompensated heart failure: cohort study evidence from Jiangxi, China.Frontiers in endocrinology · 2025Article
- Serum Malondialdehyde-Modified Low-Density Lipoprotein Level May Be a Biomarker Associated with Aortic Stiffness Among Patients Undergoing Peritoneal Dialysis.Life (Basel, Switzerland) · 2024Article
- Association between Inflammation and New-Onset Atrial Fibrillation in Acute Coronary Syndromes.Journal of clinical medicine · 2024Review
- Metabolic dysfunction and the development of physical frailty: an aging war of attrition.GeroScience · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial stiffness is a recognized predictor of cardiovascular morbidity and death. It is an early indicator of arteriosclerosis and is influenced by numerous risk factors and biological processes. The lipid metabolism is crucial and standard blood lipids, non-conventional lipid markers and lipid ratios are associated with arterial stiffness. The objective of this review was to determine which lipid metabolism marker has a greater correlation with vascular aging and arterial stiffness. Triglycerides (TG) are the standard blood lipids that have the strongest associations with arterial stiffness, and are often linked to the early stages of cardiovascular diseases, particularly in patients with low LDL-C levels. Studies often show that lipid ratios perform better overall than any of the individual variables used alone. The relation between arterial stiffness and TG/HDL-C has the strongest evidence. It is the lipid profile of atherogenic dyslipidemia that is found in several chronic cardio-metabolic disorders, and is considered one of the main causes of lipid-dependent residual risk, regardless of LDL-C concentration. Recently, the use of alternative lipid parameters has also been increasing. Both non-HDL and ApoB are very well correlated with arterial stiffness. Remnant cholesterol is also a promising alternative lipid parameter. The findings of this review suggest that the main focus should be on blood lipids and arterial stiffness, especially in individuals with cardio-metabolic disorders and residual cardiovascular risk.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.