Evidence map›Paper›PMID 36976495›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2023

Spatio-Temporal Characterization of Brain Inflammation in a Non-human Primate Stroke Model Mimicking Endovascular Thrombectomy.

Guillaume Becker, Justine Debatisse, Margaux Rivière, Claire Crola Da Silva, Maude Beaudoin-Gobert, Omer Eker, Océane Wateau, Tae Hee Cho, Marlène Wiart, Léon Tremblay and 10 more

Open access · hybridAbstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Molecular imaging of stem cell therapies in ischemic stroke.European journal of nuclear medicine and molecular imaging · 2025
    Review
  3. Article
  4. Mitochondria dysfunction, a potential cytoprotection target against ischemia-reperfusion injury in a mouse stroke model.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  5. Quantitative imaging outperforms No-reflow in predicting functional outcomes in a translational stroke model.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 3 institutions in 1 country.

Guillaume BeckerCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France. guillaume.becker@univ-lyon1.fr.ORCID 0000-0002-1714-0267
Justine DebatisseCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Margaux RivièreCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Claire Crola Da SilvaCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Maude Beaudoin-GobertLyon Neuroscience Research Center, UMR5295, INSERM U1028, CNRS, Université Claude Bernard Lyon 1, Lyon, France.
Omer EkerUMR-5220, CREATIS, CNRS, INSERM U1206, Université Lyon 1, INSA Lyon, Villeurbanne, France.
Océane WateauCynbiose SAS, Lyon, France.
Tae Hee ChoCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Marlène WiartCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Léon TremblayCognitive Neuroscience Center, CNRS UMR5229, Université Claude Bernard Lyon 1, Lyon, France.
Nicolas CostesCERMEP, Lyon, France.
Inès MéridaCERMEP, Lyon, France.
Jérôme RedoutéCERMEP, Lyon, France.
Christelle LéonCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Jean-Baptiste LangloisCERMEP, Lyon, France.
Didier Le Bars, Hospices Civils de Lyon, Lyon, France.
Sophie Lancelot, Hospices Civils de Lyon, Lyon, France.
Norbert NighoghossianCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Laura MechtouffCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Emmanuelle Canet-SoulasCarMeN Laboratory, INRAE U1397, INSERM U1060, Groupement Hospitalier Est, University Claude Bernard Lyon 1, 59 Boulevard Pinel, 69500, Lyon, Bron, France.
Université Claude Bernard Lyon 1 · FRCentre d'Exploration et de Recherche Médicale par Emission de Positons · FRHospices Civils de Lyon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reperfusion therapies in acute ischemic stroke have demonstrated their efficacy in promoting clinical recovery. However, ischemia/reperfusion injury and related inflammation remain a major challenge in patient clinical management. We evaluated the spatio-temporal evolution of inflammation using sequential clinical [

Indexed as

Brain IschemiaEncephalitisIschemic StrokeStrokeAnimalsInflammationPrimatesThrombectomyTreatment OutcomeEndovascular thrombectomyInflammationPET-MRIStrokeTSPO

Identifiers

PMID36976495
PMCPMC10275847
OpenAlexW4361190710

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.