ReviewTropical medicine and infectious disease2023
Reactive Case Detection Strategy for Malaria Control and Elimination: A 12 Year Systematic Review and Meta-Analysis from 25 Malaria-Endemic Countries.
Review in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Exploring heterogeneity in mosquito exposure and attraction and its implications for malaria transmission.PLoS computational biology · 2026Article
- Estimating probabilities of malaria importation in southern Mozambique through modellingeLife · 2026Article
- Territorial Persistence of ResidualTropical medicine and infectious disease · 2026Article
- Evaluating Thailand's malaria reactive surveillance and response strategies for malaria elimination: a mixed-method study.Infectious diseases of poverty · 2025Article
- Evaluating malaria reactive surveillance and response strategies in northeast Cambodia: a mixed-methods study.Malaria journal · 2025Article
- Advancing malaria reactive case detection in a Zambia-like setting: A modeling study.PLOS global public health · 2025Article
- Implementation and fidelity of reactive surveillance and response strategies for malaria elimination: a systematic review and meta-analysis.BMJ public health · 2025Article
- Malaria elimination in Ghana: recommendations for reactive case detection strategy implementation in a low endemic area of Asutsuare, Ghana.Malaria journal · 2024Review
- Understanding the impact of mobility on Plasmodium spp. carriage in an Amazon cross-border area with low transmission rate.PLOS global public health · 2024Article
- Editorial: Parasitism: the good, the bad and the ugly.Frontiers in veterinary science · 2023Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive case detection (RACD) is the screening of household members and neighbors of index cases reported in passive surveillance. This strategy seeks asymptomatic infections and provides treatment to break transmission without testing or treating the entire population. This review discusses and highlights RACD as a recommended strategy for the detection and elimination of asymptomatic malaria as it pertains in different countries. Relevant studies published between January 2010 and September 2022 were identified mainly through PubMed and Google Scholar. Search terms included "malaria and reactive case detection", "contact tracing", "focal screening", "case investigation", "focal screen and treat". MedCalc Software was used for data analysis, and the findings from the pooled studies were analyzed using a fixed-effect model. Summary outcomes were then presented using forest plots and tables. Fifty-four (54) studies were systematically reviewed. Of these studies, 7 met the eligibility criteria based on risk of malaria infection in individuals living with an index case < 5 years old, 13 met the eligibility criteria based on risk of malaria infection in an index case household member compared with a neighbor of an index case, and 29 met the eligibility criteria based on risk of malaria infection in individuals living with index cases, and were included in the meta-analysis. Individuals living in index case households with an average risk of 2.576 (2.540-2.612) were more at risk of malaria infection and showed pooled results of high variation heterogeneity chi-square = 235.600, (
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