ArticleStructure (London, England : 1993)2023
Structural features of the Notch ankyrin domain-Deltex WWE
Andrea A Carter, Kristen M Ramsey, Christine L Hatem, Kathryn P Sherry, Ananya Majumdar, Doug Barrick
Open access · bronzeAbstract read
In one paragraphArticle in Structure (London, England : 1993), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
6 authors at 1 institution in 1 country.
Andrea A CarterT.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
Kristen M RamseyT.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
Christine L HatemT.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
Kathryn P SherryT.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
Ananya MajumdarBiomolecular NMR Center, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA.
Doug BarrickT.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD 21218, USA. Electronic address: barrick@jhu.edu.
Johns Hopkins University · US
Funding
PROGRAM IN MOLECULAR BIOPHYSICST32GM008403 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BARRICK, DOUGLAS E. · 1990 to 2019
$13.5MREPEAT-PROTEINS;STABILITY, FOLDING KINETICS &EVOLUTIONR01GM068462 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BARRICK, DOUGLAS E. · 2005 to 2025
$6.3MStructure And Mechanism In Intracellular Notch SignalingR01GM060001 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BARRICK, DOUGLAS E. · 2001 to 2015
$3.6MThe Identity of the Notch Ankyrin Repeat Domain as a Determinant of Isoform-Specific Notch SignalingF32CA260117 · NCI · JOHNS HOPKINS UNIVERSITY · PI RAMSEY, KRISTEN MICHELLE · 2021 to 2023
$210kNCI NIH HHS F32 CA260117NIGMS NIH HHS R01 GM060001NIGMS NIH HHS R01 GM068462NIGMS NIH HHS T32 GM008403
6 · The paper itselfAbstract
The Notch signaling pathway, an important cell fate determination pathway, is modulated by the ubiquitin ligase Deltex. Here, we investigate the structural basis for Deltex-Notch interaction. We used nuclear magnetic resonance (NMR) spectroscopy to assign the backbone of the Drosophila Deltex WWE
Indexed as
AnkyrinsDrosophila ProteinsAnimalsDrosophilaMagnetic Resonance SpectroscopyMembrane ProteinsReceptors, NotchAnkyrinsDrosophila ProteinsMembrane ProteinsReceptors, Notchankyrin repeatsDeltexNMRNotchNotch signalingprotein-protein interactionsRING domainubiquitin ligaseWWE(2) motifs
Identifiers
PMID36977409
PMCPMC10338078
OpenAlexW4361002037
What Socratic holds
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LicenceTDM
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