Evidence map›Paper›PMID 36977452›Full record

ArticleNeuroImage2023

Super-resolution in brain positron emission tomography using a real-time motion capture system.

Yanis Chemli, Marc-André Tétrault, Thibault Marin, Marc D Normandin, Isabelle Bloch, Georges El Fakhri, Jinsong Ouyang, Yoann Petibon

Abstract read
In one paragraph

Article in NeuroImage, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yanis ChemliGordon Center for Medical Imaging, Department of Radiology Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; LTCI, Télécom Paris, Institut Polytechnique de Paris, France. Electronic address: ychemli@mgh.harvard.edu.
Marc-André TétraultDepartment of Computer Engineering, Université de Sherbrooke, Sherbrooke, QC, Canada. Electronic address: marc-andre.tetrault@usherbrooke.ca.
Thibault MarinGordon Center for Medical Imaging, Department of Radiology Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: tmarin@mgh.harvard.edu.
Marc D NormandinGordon Center for Medical Imaging, Department of Radiology Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: normandin@mgh.harvard.edu.
Isabelle BlochSorbonne Université, CNRS, LIP6, Paris, France; LTCI, Télécom Paris, Institut Polytechnique de Paris, France. Electronic address: isabelle.bloch@telecom-paris.fr.
Georges El FakhriGordon Center for Medical Imaging, Department of Radiology Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: elfakhri.georges@mgh.harvard.edu.
Jinsong OuyangGordon Center for Medical Imaging, Department of Radiology Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States. Electronic address: ouyang.jinsong@mgh.harvard.edu.
Yoann PetibonGordon Center for Medical Imaging, Department of Radiology Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Ultra High Resolution Brain PET Scanner for in-vivo Autoradiography ImagingU01EB027003 · NIBIB · YALE UNIVERSITY · PI EL FAKHRI, GEORGES, FONTAINE, RÉJEAN · 2018 to 2022
$4.6M
Methods for Quantitative Neuroimaging of Tau Burden inPre-symptomatic ADR01AG076153 · NIA · YALE UNIVERSITY · PI Georges El Fakhri, Marc David Normandin · 2022 to 2026
$3.0M
NIA NIH HHS R01 AG076153NIBIB NIH HHS P41 EB022544NIBIB NIH HHS U01 EB027003NIDDK NIH HHS P30 DK040561
6 · The paper itself

Abstract

Super-resolution (SR) is a methodology that seeks to improve image resolution by exploiting the increased spatial sampling information obtained from multiple acquisitions of the same target with accurately known sub-resolution shifts. This work aims to develop and evaluate an SR estimation framework for brain positron emission tomography (PET), taking advantage of a high-resolution infra-red tracking camera to measure shifts precisely and continuously. Moving phantoms and non-human primate (NHP) experiments were performed on a GE Discovery MI PET/CT scanner (GE Healthcare) using an NDI Polaris Vega (Northern Digital Inc), an external optical motion tracking device. To enable SR, a robust temporal and spatial calibration of the two devices was developed as well as a list-mode Ordered Subset Expectation Maximization PET reconstruction algorithm, incorporating the high-resolution tracking data from the Polaris Vega to correct motion for measured line of responses on an event-by-event basis. For both phantoms and NHP studies, the SR reconstruction method yielded PET images with visibly increased spatial resolution compared to standard static acquisitions, allowing improved visualization of small structures. Quantitative analysis in terms of SSIM, CNR and line profiles were conducted and validated our observations. The results demonstrate that SR can be achieved in brain PET by measuring target motion in real-time using a high-resolution infrared tracking camera.

Indexed as

Motion CapturePositron Emission Tomography Computed TomographyAlgorithmsAnimalsBrainImage Processing, Computer-AssistedMotionPhantoms, ImagingPositron-Emission Tomography3D brain PET imagingPET/CTReal timeReconstructionSuper-resolutionTracking

Identifiers

PMID36977452
PMCPMC10122782

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.