Evidence map›Paper›PMID 36978452›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Tuning the Anthranilamide Peptidomimetic Design to Selectively Target Planktonic Bacteria and Biofilm.

Rajesh Kuppusamy, Muhammad Yasir, Tsz Tin Yu, Florida Voli, Orazio Vittorio, Michael J Miller, Peter Lewis, David StC Black, Mark Willcox, Naresh Kumar

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rajesh KuppusamySchool of Chemistry, The University of New South Wales (UNSW), Sydney, NSW 2052, Australia.ORCID 0000-0001-9844-5064
Muhammad YasirSchool of Optometry and Vision Science, The University of New South Wales (UNSW), Sydney, NSW 2052, Australia.
Tsz Tin YuSchool of Chemistry, The University of New South Wales (UNSW), Sydney, NSW 2052, Australia.ORCID 0000-0002-8484-7342
Florida VoliChildren's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.
Orazio VittorioChildren's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-6610-1889
Michael J MillerSchool of Environmental and Life Sciences, College of Engineering, Science and Environment, The University of Newcastle, Newcastle, NSW 2308, Australia.
Peter LewisHunter Biological Solutions Pty Ltd., Newcastle, NSW 2310, Australia.ORCID 0000-0002-1992-062X
David StC BlackSchool of Chemistry, The University of New South Wales (UNSW), Sydney, NSW 2052, Australia.ORCID 0000-0001-9300-4737
Mark WillcoxSchool of Optometry and Vision Science, The University of New South Wales (UNSW), Sydney, NSW 2052, Australia.ORCID 0000-0003-3842-7563
Naresh KumarSchool of Chemistry, The University of New South Wales (UNSW), Sydney, NSW 2052, Australia.ORCID 0000-0002-0951-9621
UNSW Sydney · AUCancer Institute of New South Wales · AUHunter Water · AUUniversity of Newcastle Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a pressing need to develop new antimicrobials to help combat the increase in antibiotic resistance that is occurring worldwide. In the current research, short amphiphilic antibacterial and antibiofilm agents were produced by tuning the hydrophobic and cationic groups of anthranilamide peptidomimetics. The attachment of a lysine cationic group at the tail position increased activity against

Indexed as

anthranilamidebiofilmpeptidomimetics

Identifiers

PMID36978452
PMCPMC10044445
OpenAlexW4324357122

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read416
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.